{"title":"First report on the genomic characterization of Teschovirus B3 in Jiangxi Province, China.","authors":"W Liu, D Zhao, Y Peng, Z Zhou, X Tang, T Yang","doi":"10.24425/pjvs.2025.154950","DOIUrl":null,"url":null,"abstract":"<p><p>The genus Teschovirus consists of two species, Teschovirus A and Teschovirus B, with over 19 genotypes. This study sequenced the near-complete genomes of the PTV YC2 strain, previously isolated. Comparative analyses revealed nucleotide and amino acid homologies between PTV-YC2 and other PTV strains ranging from 69.7% to 93.2% and 75.6% to 99.0%, respectively. Genetic divergence analysis of the P1, polyprotein and 2C-3CD genes confirmed that PTV-YC2 belonged to the Teschovirus B species. Phylogenetic analyses showed a close evolutionary relationship between YC2 and the HuN42 strain, the prototype of the TV-B3 genotype, leading to PTV-YC2's categorization as TV-B3. This study is the first to document the prevalence of the TV-B3 genotype in Jiangxi Province, China.</p>","PeriodicalId":94175,"journal":{"name":"Polish journal of veterinary sciences","volume":"28 2","pages":"325-330"},"PeriodicalIF":0.0000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polish journal of veterinary sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24425/pjvs.2025.154950","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The genus Teschovirus consists of two species, Teschovirus A and Teschovirus B, with over 19 genotypes. This study sequenced the near-complete genomes of the PTV YC2 strain, previously isolated. Comparative analyses revealed nucleotide and amino acid homologies between PTV-YC2 and other PTV strains ranging from 69.7% to 93.2% and 75.6% to 99.0%, respectively. Genetic divergence analysis of the P1, polyprotein and 2C-3CD genes confirmed that PTV-YC2 belonged to the Teschovirus B species. Phylogenetic analyses showed a close evolutionary relationship between YC2 and the HuN42 strain, the prototype of the TV-B3 genotype, leading to PTV-YC2's categorization as TV-B3. This study is the first to document the prevalence of the TV-B3 genotype in Jiangxi Province, China.