Retrospective Comparative Analysis of Peri-Implant Grayscale Values and Marginal Bone Levels in Ultra-short Implants (5.2mm) Placed in Native Bone Versus Standard-Length Implants (>8mm) in Augmented Sites.

Sandra Marina Peppmeier, Paul Henn, Tobias Gust Graf, Peter Gehrke, Jörg Neugebauer, Paul Henn
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Abstract

Objectives: This retrospective study aimed to evaluate peri-implant marginal bone level changes and radiographic grayscale value (GSV) alterations in vertically compromised bone around ultra-short implants (5.2 mm) placed in native bone compared to standard-length implants (8-14 mm) placed in augmented sites.

Methods: The mean follow-up period was 38 months, with a maximum of 64 months. A total of 53 patients, collectively receiving 131 implants, were included. Each patient received at least both one ultra-short implant and one standard-length implant. In total 78 short implants and 53 standard length implants were placed. Standard-length implants were predominantly placed using alveolar ridge augmentation with autologous bone chips, sinus lifting, or retromolar bone block grafting. Autologous bone chips were supplemented with up to 50% bone substitute materials. Peri- implant marginal bone levels were assessed using the Distance Implant to Bone (DIB) method, while radiographic GSV served as a surrogate for bone density. All radiographic measurements were performed by two blinded evaluators using an automated x-ray overlay protocol, achieving high inter-rater reliability (intraclass correlation coefficients > 0.98). A linear mixed model, accounting for heterogeneous follow-up intervals, was applied to estimate changes in marginal bone levels (ΔMBL) and grayscale values (ΔGSV) (p < 0.05).

Results: The mean follow-up period was 38 months, with a maximum of 64 months. A total of 123 implants were assessed for changes in marginal bone level and grayscale values, representing bone density. Ultra-short implants demonstrated significantly lower marginal bone loss over the observation period (ΔMBL = -0.61 ± 0.93 mm) than standard-length implants placed in augmented bone (ΔMBL = -1.11 ± 1.26 mm; p = 0.001). Moreover, ∆GSV around ultra-short implants significantly increased (ΔGSV = 3.26 ± 20.52 a.u), whereas standard-length implants exhibited a decrease in radiographic density (ΔGSV = -0.76 ± 21.59 a.u; p = 0.009).

Conclusions: Within the limitations of this mid-term retrospective study, ultra-short implants placed in native bone exhibited statistically superior marginal bone preservation and significantly increased radiographic density when compared to standard-length implants placed in augmented sites. These results help to underscore the potential clinical advantage of opting for ultra-short implants in suitable native bone conditions to reduce the morbidity associated with extensive augmentation and less risk for periimplantitis on the long-term run in selected cases. Nevertheless, further long term, randomized investigations are warranted to confirm these findings.

超短种植体(5.2mm)与标准长度种植体(> - 8mm)在增强部位放置在天然骨上的种植体周围灰度值和边缘骨水平的回顾性比较分析
目的:本回顾性研究旨在评估放置在原生骨中的超短种植体(5.2 mm)与放置在增强部位的标准长度种植体(8-14 mm)周围垂直受损骨的种植体边缘骨水平变化和x线摄影灰度值(GSV)变化。方法:平均随访38个月,最长随访64个月。共纳入53例患者,共接受131颗种植体。每位患者至少接受了一个超短种植体和一个标准长度种植体。总共放置了78个短种植体和53个标准长度种植体。标准长度种植体主要采用牙槽嵴增强、自体骨片、窦提升或后磨牙骨块移植。自体骨芯片补充了高达50%的骨替代材料。采用种植体与骨的距离(DIB)方法评估种植体周围边缘骨水平,而x线摄影GSV作为骨密度的替代品。所有x线测量均由两名盲法评估者使用自动x线叠加方案进行,获得了较高的分级间可靠性(分级内相关系数> 0.98)。采用线性混合模型,考虑异质性随访时间间隔,估计边缘骨水平(ΔMBL)和灰度值(ΔGSV)的变化(p < 0.05)。结果:平均随访38个月,最长随访64个月。共评估123个种植体的边缘骨水平和代表骨密度的灰度值的变化。在观察期间,超短种植体的边缘骨损失(ΔMBL = -0.61±0.93 mm)明显低于标准长度种植体(ΔMBL = -1.11±1.26 mm;P = 0.001)。此外,超短种植体周围的∆GSV显著增加(ΔGSV = 3.26±20.52 a.u),而标准长度种植体的放射密度下降(ΔGSV = -0.76±21.59 a.u;P = 0.009)。结论:在这项中期回顾性研究的局限性内,与放置在增强部位的标准长度种植体相比,放置在天然骨中的超短种植体在统计学上表现出优越的边缘骨保存性,并且放射密度显著增加。这些结果有助于强调在合适的本地骨条件下选择超短种植体的潜在临床优势,以减少与广泛增加相关的发病率,并降低长期运行的特定病例中种植体周围炎的风险。然而,需要进一步的长期随机调查来证实这些发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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