Advancing Neurosurgical Oncology and AI Innovations in Latin American Brain Cancer Care: Insights from a Center of Excellence.

IF 1.6 Q3 CLINICAL NEUROLOGY
NeuroSci Pub Date : 2025-06-10 DOI:10.3390/neurosci6020054
José E Valerio, Immanuel O Olarinde, Guillermo de Jesus Aguirre Vera, Jorge Zumaeta, Noe Santiago Rea, Maria P Fernandez Gomez, Penelope Mantilla-Farfan, Andrés M Alvarez-Pinzon
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Abstract

Background: Disparities in neuro-oncological care between high-income and low- and middle-income countries (LMICs) are well documented, yet region-specific data from Latin America remain limited. This review evaluates epidemiologic trends, access to care, and systemic challenges in brain tumor management across Latin American LMICs, using Argentina as a case study. Methods: A systematic review of peer-reviewed literature was conducted focusing on brain tumor incidence, mortality, risk factors, and availability of diagnostics and treatments in Latin America. Socioeconomic, cultural, and systemic barriers were also analyzed. Results: Latin America exhibits some of the highest global brain tumor mortality rates, with Brazil reporting age-standardized rates exceeding 4.5 per 100,000. Glioblastomas are frequently diagnosed at younger ages, often in the fifth decade of life, compared to the global average. Meningioma incidence has increased by 15-20% over the last decade, yet region-wide data remain fragmented. Access to neuroimaging, neurosurgery, radiotherapy, and chemotherapy is limited, with up to 60% of patients relying solely on under-resourced public health systems. Less than 30% of hospitals in rural areas have MRI availability, and continuous professional training is infrequent. Innovative adaptations, such as awake craniotomy, are used in some LMIC centers in response to equipment scarcity. Conclusions: Brain tumor care in Latin America is hindered by limited epidemiological data, restricted access to diagnostics and treatment, and insufficient workforce training. Targeted investments in healthcare infrastructure, international educational collaborations, and policy-level reforms are critical to reducing disparities and improving outcomes in neuro-oncology across the region.

拉丁美洲脑癌护理中推进神经外科肿瘤学和人工智能创新:来自卓越中心的见解。
背景:高收入国家与低收入和中等收入国家(LMICs)在神经肿瘤治疗方面的差异有充分的文献记录,但拉丁美洲地区的特定数据仍然有限。本综述以阿根廷为例,评估了拉丁美洲中低收入国家脑肿瘤管理的流行病学趋势、护理可及性和系统性挑战。方法:对同行评议文献进行系统综述,重点关注拉丁美洲脑肿瘤发病率、死亡率、危险因素以及诊断和治疗的可得性。还分析了社会经济、文化和体制障碍。结果:拉丁美洲是全球脑肿瘤死亡率最高的国家之一,巴西报告的年龄标准化死亡率超过每10万人4.5人。与全球平均水平相比,胶质母细胞瘤通常在更年轻的年龄被诊断出来,通常在生命的第五个十年。脑膜瘤发病率在过去十年中增加了15-20%,但区域范围内的数据仍然不完整。获得神经影像学、神经外科手术、放疗和化疗的机会有限,多达60%的患者完全依赖资源不足的公共卫生系统。农村地区只有不到30%的医院拥有核磁共振成像,而且持续的专业培训也很少。一些LMIC中心采用了一些创新的适应措施,如清醒开颅术,以应对设备短缺。结论:拉丁美洲的脑肿瘤护理受到流行病学数据有限、诊断和治疗获取受限以及劳动力培训不足的阻碍。在医疗基础设施、国际教育合作和政策层面的改革方面进行有针对性的投资,对于缩小该地区神经肿瘤学的差异和改善结果至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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