{"title":"Small Toxic Molecule Detection and Elimination Using Molecularly Imprinted Polymers (MIPs).","authors":"Min Seok Kang, Jin-Ho Lee, Ki Su Kim","doi":"10.3390/bios15060393","DOIUrl":null,"url":null,"abstract":"<p><p>Molecularly imprinted polymers (MIPs) provide selective, robust, and cost-effective platforms for the detection and removal of small toxic molecules in environmental, food, and biomedical contexts. This review offers a comprehensive overview of recent advancements in MIP-based systems, emphasizing critical design factors such as template selection, functional monomers, polymerization methods, and binding kinetics. The impact of these parameters on improving sensitivity, selectivity, and reusability is thoroughly examined. Additionally, current advantages, limitations, and enduring challenges are addressed. By highlighting emerging strategies and interdisciplinary innovations, this work aims to guide the development of more efficient and sustainable technologies for small-molecule toxin detection and remediation.</p>","PeriodicalId":48608,"journal":{"name":"Biosensors-Basel","volume":"15 6","pages":""},"PeriodicalIF":4.9000,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12190631/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biosensors-Basel","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.3390/bios15060393","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Molecularly imprinted polymers (MIPs) provide selective, robust, and cost-effective platforms for the detection and removal of small toxic molecules in environmental, food, and biomedical contexts. This review offers a comprehensive overview of recent advancements in MIP-based systems, emphasizing critical design factors such as template selection, functional monomers, polymerization methods, and binding kinetics. The impact of these parameters on improving sensitivity, selectivity, and reusability is thoroughly examined. Additionally, current advantages, limitations, and enduring challenges are addressed. By highlighting emerging strategies and interdisciplinary innovations, this work aims to guide the development of more efficient and sustainable technologies for small-molecule toxin detection and remediation.
Biosensors-BaselBiochemistry, Genetics and Molecular Biology-Clinical Biochemistry
CiteScore
6.60
自引率
14.80%
发文量
983
审稿时长
11 weeks
期刊介绍:
Biosensors (ISSN 2079-6374) provides an advanced forum for studies related to the science and technology of biosensors and biosensing. It publishes original research papers, comprehensive reviews and communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Electronic files and software regarding the full details of the calculation or experimental procedure, if unable to be published in a normal way, can be deposited as supplementary electronic material.