{"title":"Time to retire the term “atypical Parkinsonism”","authors":"Junaid H. Siddiqui , Lawrence I. Golbe","doi":"10.1016/j.parkreldis.2025.107927","DOIUrl":null,"url":null,"abstract":"<div><div>Variable and imprecise use of the term “Parkinsonism” has produced confusion among patients, clinicians, caregivers, and researchers. The term “atypical Parkinsonism” can be dispiriting and even demeaning to patients. We therefore propose a slight terminological revision for Parkinsonian disorders to eliminate the terms “typical” and “atypical” and to confine the term “Parkinsonism” to the phenotypic syndrome and not to disease entities. We also suggest replacing the “atypical Parkinsonism” term with “Parkinson-like disorders” to emphasize that it is not PD but does resemble it at some level. “Parkinson-like disorders” would comprise the primary neurodegenerative Parkinsonian disorders other than PD, chiefly MSA, DLB, PSP, and CBD, and would be consistent with the existing neurologic terms, “Huntington's disease-like,” “polio-like,” and “stroke-like.” We would continue the practice of referring to the non-degenerative Parkinsonian disorders as “secondary Parkinsonian disorders.”</div></div>","PeriodicalId":19970,"journal":{"name":"Parkinsonism & related disorders","volume":"137 ","pages":"Article 107927"},"PeriodicalIF":3.1000,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Parkinsonism & related disorders","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1353802025006686","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Variable and imprecise use of the term “Parkinsonism” has produced confusion among patients, clinicians, caregivers, and researchers. The term “atypical Parkinsonism” can be dispiriting and even demeaning to patients. We therefore propose a slight terminological revision for Parkinsonian disorders to eliminate the terms “typical” and “atypical” and to confine the term “Parkinsonism” to the phenotypic syndrome and not to disease entities. We also suggest replacing the “atypical Parkinsonism” term with “Parkinson-like disorders” to emphasize that it is not PD but does resemble it at some level. “Parkinson-like disorders” would comprise the primary neurodegenerative Parkinsonian disorders other than PD, chiefly MSA, DLB, PSP, and CBD, and would be consistent with the existing neurologic terms, “Huntington's disease-like,” “polio-like,” and “stroke-like.” We would continue the practice of referring to the non-degenerative Parkinsonian disorders as “secondary Parkinsonian disorders.”
期刊介绍:
Parkinsonism & Related Disorders publishes the results of basic and clinical research contributing to the understanding, diagnosis and treatment of all neurodegenerative syndromes in which Parkinsonism, Essential Tremor or related movement disorders may be a feature. Regular features will include: Review Articles, Point of View articles, Full-length Articles, Short Communications, Case Reports and Letter to the Editor.