Presumed Solitary Circumscribed Retinal Astrocytic Proliferation: A Case Report.

IF 1.2 Q3 OPHTHALMOLOGY
Journal of Current Ophthalmology Pub Date : 2025-06-05 eCollection Date: 2024-07-01 DOI:10.4103/joco.joco_136_24
Mojtaba Abrishami, Daniel J Weisbrod, Hatem Krema
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引用次数: 0

Abstract

Purpose: To report a case of presumed solitary circumscribed retinal astrocytic proliferation (PSCRAP) diagnosed through multimodal imaging.

Methods: A single case report documented with multimodal imaging.

Results: A 41-year-old asymptomatic female was referred for a second opinion regarding whitish retinal lesions in her left eye, first identified by her local optometrist 8 years prior. Her history included Hashimoto thyroiditis, with no personal or family history of tuberous sclerosis complex or neurofibromatosis. Visual acuity was 20/20 in both eyes. Fundoscopy of the left eye revealed two pearly white avascular retinal masses. Spectral-domain optical coherence tomography (SD-OCT) showed hyperreflective intraretinal masses with optical shadowing. Optical coherence tomography angiography (OCTA) demonstrated a signal void in the retinal vascular plexuses. Fundus autofluorescence showed moderate hyperautofluorescence. The lesions remained stable over 3 months.

Conclusions: PSCRAP is a rare, benign retinal tumor. Multimodal imaging, including SD-OCT and OCTA, is essential for accurate diagnosis, showing unique features such as separation from the retinal nerve fiber layer and lack of intrinsic vascularity. Our observation of two lesions raises questions about the solitary nature of this condition. Continued documentation may be necessary to differentiate from simulating lesions that may undergo subsequent growth.

假定孤立性局限性视网膜星形细胞增生1例。
目的:报告一例经多模态成像诊断为孤立性局限性视网膜星形细胞增生(PSCRAP)。方法:用多模态影像记录一例病例。结果:一名41岁无症状女性因左眼发白色视网膜病变被转诊,该病变于8年前由当地验光师首次发现。病史包括桥本甲状腺炎,无结节性硬化症或神经纤维瘤病的个人或家族史。双眼视力均为20/20。左眼眼底镜检查发现两个珍珠白色的无血管视网膜肿块。光谱域光学相干断层扫描(SD-OCT)显示视网膜内高反射肿块伴光学阴影。光学相干断层血管造影(OCTA)显示视网膜血管丛信号空洞。眼底自体荧光显示中度高自体荧光。病变在3个月内保持稳定。结论:PSCRAP是一种罕见的良性视网膜肿瘤。包括SD-OCT和OCTA在内的多模态成像对准确诊断至关重要,它们显示出独特的特征,如与视网膜神经纤维层分离,缺乏内在血管。我们对两个病变的观察提出了关于这种情况的孤立性的问题。可能需要继续记录以区分可能经历后续生长的模拟病变。
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来源期刊
CiteScore
2.50
自引率
6.70%
发文量
45
审稿时长
8 weeks
期刊介绍: Peer Review under the responsibility of Iranian Society of Ophthalmology Journal of Current Ophthalmology, the official publication of the Iranian Society of Ophthalmology, is a peer-reviewed, open-access, scientific journal that welcomes high quality original articles related to vision science and all fields of ophthalmology. Journal of Current Ophthalmology is the continuum of Iranian Journal of Ophthalmology published since 1969.
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