Seyed Ali Tabatabaei, Ahmad Masoumi, Arash Mirzaei, Reza Mirshahi, Bita Momenaei, Faezeh Moghimpour Bijani, Ali Rashidinia, Mohammadreza Nazari, Mohammad Ahadifard, Zahra Mahdizad, Samer Habeel, Seyed Mahbod Baharnoori, Mohammad Soleimani
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引用次数: 0
Abstract
Purpose: To describe the demographic characteristics, etiology, microbiological spectrum, and antibiotic sensitivity patterns in patients with endophthalmitis.
Methods: This is a retrospective case series spanning from May 2012 to September 2018. All included patients were diagnosed with endophthalmitis and confirmed by laboratory tests. Data were collected on patient demographics, types of endophthalmitis, and microbiologic and medical records.
Results: Nine hundred ninety-two records of patients with endophthalmitis were assessed. Of the total cases, 657 patients (66.2%) were male, whereas 335 (33.8%) were female. The mean age of the patients was 57.2 ± 22.8 years and ranged from 2 to 95 years. The type of endophthalmitis was acute postcataract surgery (44.4%), posttraumatic (26.7%), chronic postcataract surgery (6.6%), endogenous (6.4%), postintravitreal injection (5.0%), keratitis-associated (3.6%), postvitrectomy (2.7%), bleb-associated (2.4%), postkeratoplasty (1.9%), and device-related (0.1%). The most frequently isolated organisms were Staphylococcus epidermidis (11.7%), followed by Streptococcus pneumoniae (5.2%) and Streptococcus viridans (5.1%). Antibiotic susceptibility testing in patients with acute postcataract surgery endophthalmitis showed variable sensitivity of S. epidermidis isolates to vancomycin (81.4%), ciprofloxacin (76.2%), and levofloxacin (75.0%). In patients with posttraumatic endophthalmitis, high rates of zone 1 injury (61.5%), traumatic cataract (67.9%), and intraocular foreign body (IOFB) (29.8%) were observed.
Conclusions: S. epidermidis is the most common causative pathogen in patients with endophthalmitis, its increasing resistance to vancomycin and fluoroquinolones may pose some challenges to the treatment of endophthalmitis in the future. Regarding the presence of IOFB, zone 1 injury, and traumatic cataracts that might be associated with an increased risk of posttraumatic endophthalmitis, it is better to consider these aspects in penetrating eye injuries.
期刊介绍:
Peer Review under the responsibility of Iranian Society of Ophthalmology Journal of Current Ophthalmology, the official publication of the Iranian Society of Ophthalmology, is a peer-reviewed, open-access, scientific journal that welcomes high quality original articles related to vision science and all fields of ophthalmology. Journal of Current Ophthalmology is the continuum of Iranian Journal of Ophthalmology published since 1969.