Necrotic skin reaction following the administration of intramuscular injections of long-acting cabotegravir/rilpivirine and alternatively-sourced testosterone.

IF 1.4 4区 医学 Q4 IMMUNOLOGY
Shahid Bukhari, Ruth Byrne, Yemi Daramola, Christina Antoniadi, Marta Boffito
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引用次数: 0

Abstract

In this case, we describe a 52-year-old man who was switched to long-acting cabotegravir/rilpivirine (CAB/RPV LA) injectable antiretroviral therapy (ART) on a background of well-controlled HIV. He subsequently developed a painful and swollen area on his right ventrogluteal region 10 days after his first CAB/RPV LA injections when he injected alternatively sourced testosterone in the same region. Examination findings showed a firm and defined lump with ecchymosis noted on the skin overlying. His initial blood results did not show any gross abnormalities and an ultrasound of the area was equivocal. After being reviewed in ambulatory care, the emergency department and an outpatient plastic surgery clinic settings over the course of 3 weeks, the swelling and skin changes gradually resolved. He was then switched back to oral ART on subsequent review.

肌肉注射长效卡替格拉韦/利匹韦林和替代来源睾酮后的皮肤坏死反应。
在本病例中,我们描述了一名52岁的男性,他在HIV控制良好的背景下改用长效卡博特格拉韦/利匹韦林(CAB/RPV LA)注射抗逆转录病毒治疗(ART)。随后,在首次注射CAB/RPV LA后10天,患者在同一区域注射了替代来源的睾酮,右侧腹肌区出现疼痛和肿胀。检查结果显示一坚硬而清晰的肿块,上面的皮肤有淤斑。他最初的血液检查结果没有显示出任何明显的异常,该区域的超声检查结果也模棱两可。在门诊、急诊科和整形外科门诊复查3周后,肿胀和皮肤变化逐渐消退。在随后的复查中,他被转回口服抗逆转录病毒治疗。
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来源期刊
CiteScore
2.60
自引率
7.10%
发文量
144
审稿时长
3-6 weeks
期刊介绍: The International Journal of STD & AIDS provides a clinically oriented forum for investigating and treating sexually transmissible infections, HIV and AIDS. Publishing original research and practical papers, the journal contains in-depth review articles, short papers, case reports, audit reports, CPD papers and a lively correspondence column. This journal is a member of the Committee on Publication Ethics (COPE).
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