The Role of Osteoporosis in Total Hip Arthroplasty Periprosthetic Fractures and Current Management Strategies: a Review.

IF 4.3 2区医学

Current Osteoporosis Reports Pub Date : 2025-06-23 DOI:10.1007/s11914-025-00922-5

Jordan Bauer, Joseph Duero, Adam Lindsay

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Abstract

Purpose of review: This review provides a background on osteoporosis, describes the relationship between osteoporosis and periprosthetic fracture following total hip arthroplasty (THA), as well as to discusses current management strategies and future directions for improved patient outcomes.

Recent findings: Periprosthetic fracture of the hip is among one of the most common reasons for revision following THA and occurs in 0.1-3.5% of individuals. Periprosthetic fractures come with significant cost, morbidity, and future mortality. Risks for periprosthetic fractures following THA include female sex, older age, rheumatoid arthritis, and osteoporosis. Recent works have demonstrated that osteoporosis plays an important role in the rising prevalence of periprosthetic fractures following THA. This review characterizes the interplay between osteoporosis and periprosthetic hip fractures following THA with emphasis placed upon the pathophysiology of osteoporosis, the mechanisms by which osteoporosis promote periprosthetic fractures, management of such fractures, and the potential for future therapies.

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骨质疏松症在全髋关节置换术周围骨折中的作用及当前的处理策略：综述。

综述目的：本文综述了骨质疏松症的研究背景，描述了骨质疏松症与全髋关节置换术（THA）后假体周围骨折的关系，并讨论了目前的治疗策略和未来改善患者预后的方向。最近发现：髋关节假体周围骨折是THA术后翻修最常见的原因之一，发生率为0.1-3.5%。假体周围骨折具有显著的成本、发病率和未来死亡率。THA术后假体周围骨折的风险包括女性、年龄较大、类风湿关节炎和骨质疏松症。最近的研究表明，骨质疏松症在THA术后假体周围骨折发生率上升中起重要作用。本文综述了髋关节置换术后骨质疏松症与髋关节假体周围骨折之间的相互作用，重点介绍了骨质疏松症的病理生理、骨质疏松症促进假体周围骨折的机制、此类骨折的处理以及未来治疗的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Osteoporosis Reports ENDOCRINOLOGY & METABOLISM-

CiteScore

8.40

自引率

2.30%

发文量

期刊介绍： This journal intends to provide clear, insightful, balanced contributions by international experts that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of osteoporosis. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as current and future therapeutics, epidemiology and pathophysiology, and evaluation and management. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.