Innovations and Emerging Therapies in Atopic Dermatitis Part 1.

IF 1.9 Q3 ALLERGY

Current Treatment Options in Allergy Pub Date : 2025-01-01 Epub Date: 2025-05-07 DOI:10.1007/s40521-025-00390-3

Robyn Okereke, Eric Simpson

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引用次数: 0

Abstract

Purpose of review: The purpose of this review is to discuss the innovative aspects of present and newer therapies used for the treatment of AD, as well as to highlight the characteristics of emerging treatments. We also compare alternative systemic therapies. The novelties surrounding systemic therapies will be highlighted in this first review (part 1), while innovations in topical therapies will be discussed in a subsequent review (part 2).

Recent findings: The treatment landscape of atopic dermatitis has been quickly evolving in recent history. The treatment framework of AD is shifting from broad suppression of the inflammatory response to targeted molecular therapy.

Summary: Overall, this therapeutic shift does appear to correlate with a superior efficacy and safety profile, though we also highlight encountered shortcomings when assessing long-term and real-world data of systemic therapies. Despite significant recent advances, future studies are needed to optimize formulations and performance of systemic therapies for AD.

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综述目的：本综述的目的是讨论用于治疗阿尔茨海默病的现有和新疗法的创新方面，并强调新兴疗法的特点。我们还比较了不同的全身疗法。在第一篇综述（第1部分）中，将重点介绍全身疗法的创新，而局部疗法的创新将在随后的综述（第2部分）中讨论。最近的研究结果：特应性皮炎的治疗前景在最近的历史中迅速发展。阿尔茨海默病的治疗框架正在从广泛抑制炎症反应转向靶向分子治疗。总结：总的来说，这种治疗方法的转变似乎与优越的疗效和安全性相关，尽管我们也强调了在评估全身治疗的长期和实际数据时遇到的缺点。尽管最近取得了重大进展，但需要进一步的研究来优化阿尔茨海默病全身治疗的配方和性能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Treatment Options in Allergy Medicine-Medicine (miscellaneous)

CiteScore

2.50

自引率

0.00%

发文量

期刊介绍： Current Treatment Options in Allergy will focus on the latest advances in the treatment of allergic disorders. Designed for physicians, this journal offers expert reviews on the management of skin allergies, venom allergies, rhinitis, asthma, food allergies, drug allergies, atopic dermatitis, allergy prevention, and anaphylaxis.Articles cover a range of established and emerging treatment options. We accomplish this by having experts present the latest research, assess the efficacy of available treatment options, and discuss special considerations. We ensure that the journal content includes current, emerging research and suggest articles of special interest.