[A clinical control study of bleeding tendency and risk factors in patients with oral antithrombotic drugs after dental extractions].

Q4 Medicine
上海口腔医学 Pub Date : 2025-04-01
Qi Luo, Zhu Zhu, Huan Shi, Qin Zhou, Chuangqi Yu
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引用次数: 0

Abstract

Purpose: To explore the bleeding tendency and related risk factors of patients with or without oral antithrombotic drugs after tooth extraction, in order to provide theoretical reference for perioperative management of tooth extraction.

Methods: A cohort study was conducted among patients who attended the Cardiovascular Tooth Extraction Specialist Clinic of Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine from March 2023 to June 2023. The patients were divided into experimental group (medication group) and control group (no medication group) according to whether they took antithrombotic drugs for a long time. Teeth extraction was performed under ECG monitoring and postoperative bleeding was followed up to analyze the incidence of bleeding and related risk factors. SPSS 22.0 software package was used for data analysis.

Results: A total of 645 patients were included, including 305 patients in the medication group and 340 patients in the non-medication group. Bleeding events occurred in 17 cases (5.6%, 17/305) in the medication group and 1 (0.3%, 1/340) in the non-medication group, with significant difference between the two groups (P<0.01). Binary logistic regression analysis showed that old age (OR: 4.089, 95%CI: 1.351-12.374, P=0.013) had a significant positive effect on postoperative bleeding.

Conclusions: Oral antithrombotic drugs and advanced age are the risk factors for postoperative bleeding in patients with cardiovascular diseases undergoing tooth extractions.

[拔牙后口服抗栓药物患者出血倾向及危险因素的临床对照研究]。
目的:探讨使用或不使用口服抗栓药物患者拔牙后出血倾向及相关危险因素,为拔牙围手术期管理提供理论参考。方法:对2023年3月至2023年6月在上海交通大学医学院附属上海第九人民医院心血管拔牙专科门诊就诊的患者进行队列研究。根据患者是否长期服用抗血栓药物分为实验组(服药组)和对照组(未服药组)。在心电图监测下拔牙,术后随访出血情况,分析出血发生率及相关危险因素。采用SPSS 22.0软件包进行数据分析。结果:共纳入645例患者,其中用药组305例,非用药组340例。用药组出血17例(5.6%,17/305),非用药组出血1例(0.3%,1/340),两组比较差异有统计学意义(P<0.01)。二元logistic回归分析显示,老年患者(OR: 4.089, 95%CI: 1.351-12.374, P=0.013)对术后出血有显著的积极影响。结论:口服抗栓药物和高龄是心血管疾病患者拔牙术后出血的危险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
上海口腔医学
上海口腔医学 Medicine-Medicine (all)
CiteScore
0.30
自引率
0.00%
发文量
5299
期刊介绍: "Shanghai Journal of Stomatology (SJS)" is a comprehensive academic journal of stomatology directed by Shanghai Jiao Tong University and sponsored by the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine. The main columns include basic research, clinical research, column articles, clinical summaries, reviews, academic lectures, etc., which are suitable for reference by clinicians, scientific researchers and teaching personnel at all levels engaged in oral medicine.
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