Unilateral contralesional versus bilateral repetitive transcranial magnetic stimulation for patients with post stroke dysphagia: a randomized controlled study.

IF 2.7 4区 医学 Q2 CLINICAL NEUROLOGY
Basem Hamdy Fouda, Ahmed Mostafa Kishk
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引用次数: 0

Abstract

Background: Dysphagia is a frequent and challenging complication after stroke, severely impacting both recovery and quality of life. Conventional rehabilitation approaches often yield limited results, underscoring the need for novel treatments. This work compared the effectiveness of two different repetitive transcranial magnetic stimulation (rTMS) approaches in enhancing swallowing function in post-stroke dysphagia (PSD).

Methods: This prospective, randomized, controlled trial was conducted with 60 patients, 18-80 years old, diagnosed with acute ischemic stroke and suffered from PSD. Participants were randomized equally to three groups: Group 1 received bilateral facilitatory rTMS targeting both hemispheres, Group 2 received unilateral facilitatory rTMS on the contralesional hemisphere, and Group 3 received sham rTMS.

Results: Motor threshold (MT) scores were similar across the three groups at baseline (date 0). At follow-up, Group 1 showed significantly lower MT scores than Group 3 at dates 1 and 3 (P < 0.05), with no significant difference between Group 2 and Groups 1 and 3. At date 2, Group 1 had significantly lower MT scores than both Groups 2 and 3 (P < 0.05), while scores between Group 2 and Group 3 were comparable. MT was comparable among the groups at date 0, 1, 2, and 3. For the Modified Rankin Scale, at date 3, Groups 1 and 2 had significantly lower scores than Group 3, with no significant difference between Groups 1 and 2.

Conclusions: Bilateral facilitatory rTMS is an effective and safe intervention for improving swallowing function in PSD.

单侧对侧与双侧重复经颅磁刺激治疗卒中后吞咽困难患者:一项随机对照研究。
背景:吞咽困难是卒中后常见且具有挑战性的并发症,严重影响患者的康复和生活质量。传统的康复方法往往产生有限的结果,强调需要新的治疗方法。本研究比较了两种不同的重复经颅磁刺激(rTMS)方法在增强脑卒中后吞咽困难(PSD)患者吞咽功能方面的有效性。方法:本前瞻性、随机、对照试验纳入60例18-80岁的急性缺血性脑卒中患者,并伴有PSD。参与者被随机分为三组:组1接受针对双侧半球的双侧促进性rTMS,组2接受针对对侧半球的单侧促进性rTMS,组3接受假rTMS。结果:运动阈值(MT)评分在基线(日期0)时在三组之间相似。在随访中,组1在第1天和第3天的MT评分明显低于组3 (P)。结论:双侧辅助rTMS是改善PSD患者吞咽功能的有效和安全的干预措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Neurological Sciences
Neurological Sciences 医学-临床神经学
CiteScore
6.10
自引率
3.00%
发文量
743
审稿时长
4 months
期刊介绍: Neurological Sciences is intended to provide a medium for the communication of results and ideas in the field of neuroscience. The journal welcomes contributions in both the basic and clinical aspects of the neurosciences. The official language of the journal is English. Reports are published in the form of original articles, short communications, editorials, reviews and letters to the editor. Original articles present the results of experimental or clinical studies in the neurosciences, while short communications are succinct reports permitting the rapid publication of novel results. Original contributions may be submitted for the special sections History of Neurology, Health Care and Neurological Digressions - a forum for cultural topics related to the neurosciences. The journal also publishes correspondence book reviews, meeting reports and announcements.
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