Fourier ptychography microscopy for digital pathology.

IF 1.9 4区 工程技术 Q3 MICROSCOPY
Fraser Eadie, Laura Copeland, Giuseppe Di Caprio, Gail McConnell, Akhil Kallepalli
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引用次数: 0

Abstract

Fourier ptychography microscopy (FPM) has made significant progress since its invention in 2013, thanks to its adaptable nature, high resolution, and vast field-of-view capabilities. FPM is used in various medical applications across multiple optical wavelengths, from automated digital pathology to radiology and ultraviolet label-free imaging. This review explores the fundamental physical and computational concepts that have driven advancements in digital pathology using FPM. A crucial part of the progress has been the development of computational algorithms, which have directly contributed to the improvements in FPM. We evaluate early-stage algorithms like the Gerchberg-Saxton and highlight how phase-retrieval and deep-learning advancements have propelled FPM forward. Additionally, we discuss the impact of these algorithms on digital pathology for potential automated diagnosis, providing a comprehensive explanation of their influence on medical imaging and offering insights into future research directions.

用于数字病理学的傅立叶平面摄影显微镜。
傅里叶平面摄影显微镜(FPM)自2013年发明以来,由于其适应性、高分辨率和广阔的视场能力,已经取得了重大进展。FPM用于多种光学波长的各种医疗应用,从自动数字病理学到放射学和紫外无标签成像。这篇综述探讨了使用FPM推动数字病理学进步的基本物理和计算概念。这一进步的一个关键部分是计算算法的发展,它直接促进了FPM的改进。我们评估了Gerchberg-Saxton等早期算法,并强调了相位检索和深度学习的进步是如何推动FPM向前发展的。此外,我们还讨论了这些算法对数字病理学潜在自动诊断的影响,全面解释了它们对医学成像的影响,并为未来的研究方向提供了见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of microscopy
Journal of microscopy 工程技术-显微镜技术
CiteScore
4.30
自引率
5.00%
发文量
83
审稿时长
1 months
期刊介绍: The Journal of Microscopy is the oldest journal dedicated to the science of microscopy and the only peer-reviewed publication of the Royal Microscopical Society. It publishes papers that report on the very latest developments in microscopy such as advances in microscopy techniques or novel areas of application. The Journal does not seek to publish routine applications of microscopy or specimen preparation even though the submission may otherwise have a high scientific merit. The scope covers research in the physical and biological sciences and covers imaging methods using light, electrons, X-rays and other radiations as well as atomic force and near field techniques. Interdisciplinary research is welcome. Papers pertaining to microscopy are also welcomed on optical theory, spectroscopy, novel specimen preparation and manipulation methods and image recording, processing and analysis including dynamic analysis of living specimens. Publication types include full papers, hot topic fast tracked communications and review articles. Authors considering submitting a review article should contact the editorial office first.
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