Sophie Ettinger, John C Castle, Julian Robinson, Nicolas Pinto-Sander, Daniel Richardson
{"title":"The characteristics of men who have sex with men with <i>Blastocystis</i>: A systematic review.","authors":"Sophie Ettinger, John C Castle, Julian Robinson, Nicolas Pinto-Sander, Daniel Richardson","doi":"10.1177/09564624251349910","DOIUrl":null,"url":null,"abstract":"<p><p>Objective<i>Blastocystis</i> is an enteric parasite which can cause gastrointestinal symptoms and may be sexually transmissible in men who have sex with men (MSM). This review aimed to explore the characteristics of MSM with <i>Blastocystis</i>.MethodFive bibliographical databases (CINAHL, EMBASE, MEDLINE, EMCARE, Cochrane-central) were searched for manuscripts which explored the characteristics of MSM with <i>Blastocystis</i> written in English, French or Spanish in October 2024. Following the initial search, duplicates were removed, and two authors independently conducted a full text review and risk of bias assessment using the Joanna Briggs Institute toolkits. Narrative data were synthesised to generate themes. The protocol was registered on PROSPERO(ID:CRD42024582946).ResultsFourteen manuscripts were included in this review; from Australia (<i>n</i> = 2), Spain (<i>n</i> = 2), Denmark (<i>n</i> = 2), USA (<i>n</i> = 2), UK(<i>n</i> = 1), Italy (<i>n</i> = 1), France (<i>n</i> = 1), Germany (<i>n</i> = 1), Canada (<i>n</i> = 1) & China (<i>n</i> = 1) published between 1988 and 2022. The manuscripts were case-reports (<i>n</i> = 2), case-series (<i>n</i> = 1) and cross-sectional studies (<i>n</i> = 11) and included 693 MSM who tested positive for <i>Blastocystis.</i> The majority of MSM in this review were living with HIV which either represents a biological, a behavioural (surrogate) characteristic or a confounding association. This review also highlighted demographic (being asymptomatic), behavioural (multiple sexual partners, recent (tropical) travel, oral-anal sex) and infection (co-infection with STI [<i>N</i>. <i>gonorrhoeae, C</i>. <i>trachomatis</i>], co-infection with other sexually transmissible enteric pathogens [<i>Salmonella spp., Campylobacter</i> spp.<i>, E.coli, E</i>. <i>histolytica, G</i>. <i>duodenalis, Cryptosporidium</i> spp.], co-infection with intestinal spirochaetosis<i>,</i> co-infection with a non-pathogenic enteric parasite) characteristics of MSM who tested positive for <i>Blastocystis.</i>ConclusionThis review serves as a resource for future public health control strategies, clinical guidelines and research to understand the sexual transmissibility of <i>Blastocystis</i> in MSM.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251349910"},"PeriodicalIF":1.4000,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of STD & AIDS","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/09564624251349910","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
ObjectiveBlastocystis is an enteric parasite which can cause gastrointestinal symptoms and may be sexually transmissible in men who have sex with men (MSM). This review aimed to explore the characteristics of MSM with Blastocystis.MethodFive bibliographical databases (CINAHL, EMBASE, MEDLINE, EMCARE, Cochrane-central) were searched for manuscripts which explored the characteristics of MSM with Blastocystis written in English, French or Spanish in October 2024. Following the initial search, duplicates were removed, and two authors independently conducted a full text review and risk of bias assessment using the Joanna Briggs Institute toolkits. Narrative data were synthesised to generate themes. The protocol was registered on PROSPERO(ID:CRD42024582946).ResultsFourteen manuscripts were included in this review; from Australia (n = 2), Spain (n = 2), Denmark (n = 2), USA (n = 2), UK(n = 1), Italy (n = 1), France (n = 1), Germany (n = 1), Canada (n = 1) & China (n = 1) published between 1988 and 2022. The manuscripts were case-reports (n = 2), case-series (n = 1) and cross-sectional studies (n = 11) and included 693 MSM who tested positive for Blastocystis. The majority of MSM in this review were living with HIV which either represents a biological, a behavioural (surrogate) characteristic or a confounding association. This review also highlighted demographic (being asymptomatic), behavioural (multiple sexual partners, recent (tropical) travel, oral-anal sex) and infection (co-infection with STI [N. gonorrhoeae, C. trachomatis], co-infection with other sexually transmissible enteric pathogens [Salmonella spp., Campylobacter spp., E.coli, E. histolytica, G. duodenalis, Cryptosporidium spp.], co-infection with intestinal spirochaetosis, co-infection with a non-pathogenic enteric parasite) characteristics of MSM who tested positive for Blastocystis.ConclusionThis review serves as a resource for future public health control strategies, clinical guidelines and research to understand the sexual transmissibility of Blastocystis in MSM.
期刊介绍：
The International Journal of STD & AIDS provides a clinically oriented forum for investigating and treating sexually transmissible infections, HIV and AIDS. Publishing original research and practical papers, the journal contains in-depth review articles, short papers, case reports, audit reports, CPD papers and a lively correspondence column. This journal is a member of the Committee on Publication Ethics (COPE).
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