Electrocardiogram indicators of right ventricular dilation in repaired tetralogy of Fallot patients.

IF 1.8 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Expert Review of Cardiovascular Therapy Pub Date : 2025-06-23 DOI:10.1080/14779072.2025.2524566

Uchina Hiya, Tomoyuki Kabutoya, Yasushi Imai, Kana Kubota, Kenta Fujimura, Akiko Yokomizo, Mitsuru Seki, Kazuomi Kario

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引用次数: 0

Abstract

Background: Patients with surgically repaired tetralogy of Fallot (rTOF) often develop chronic pulmonary regurgitation (PR), necessitating pulmonary valve replacement (PVR). While cardiac MRI is crucial for PVR timing, its availability is limited. This study evaluates electrocardiographic (ECG) findings - specifically the R-wave amplitude in lead V1 (V1R) and the sum of the R-wave amplitude in lead V1 and the deepest S-wave amplitude in lead V5 or V6 (V1R + V5S or V6S) - as predictors of cardiac MRI findings.

Patients and methods: We retrospectively analyzed 35 rTOF patients (mean age 34 ± 9 years; 60% male) who underwent cardiac MRI from 2019 to 2022, assessing correlations between ECG parameters (V1R, V1R + V5S or V6S, and QRS duration) and MRI findings (RVESVI and RVEDVI).

Results: V1R showed significant correlation with RVESVI (r = 0.486, p = 0.003) and was notably higher in patients with RVESVI ≥80 mL/m². A V1R cutoff of 20 mm identified RVESVI ≥80 mL/m² with 67% sensitivity and 77% specificity.

Conclusions: V1R on ECG may help predict the need for cardiac MRI, aiding in the timely PVR planning for rTOF patients.

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修复后法洛四联症患者右心室扩张的心电图指标。

背景：手术修复的法洛四联症（rTOF）患者经常发生慢性肺反流（PR），需要肺动脉瓣置换术（PVR）。虽然心脏MRI对PVR的时机至关重要，但其可用性有限。本研究评估心电图（ECG）的结果——特别是V1导联的r波振幅（V1R）和V1导联的r波振幅和V5或V6导联的最深s波振幅（V1R + V5S或V6S）的总和——作为心脏MRI结果的预测因子。患者和方法：回顾性分析35例rTOF患者(平均年龄34±9岁；在2019年至2022年期间接受心脏MRI（60%男性），评估ECG参数（V1R， V1R + V5S或V6S， QRS持续时间）与MRI结果（RVESVI和RVEDVI）之间的相关性。结果：V1R与RVESVI有显著相关性（r = 0.486, p = 0.003），且RVESVI≥80 mL/m2的患者V1R较高。V1R截断值为20 mm时，RVESVI≥80 mL/m2的敏感性为67%，特异性为77%。结论：心电图上的V1R有助于预测心脏MRI的需要，有助于rTOF患者及时制定PVR计划。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Expert Review of Cardiovascular Therapy CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

3.70

自引率

0.00%

发文量

期刊介绍： Expert Review of Cardiovascular Therapy (ISSN 1477-9072) provides expert reviews on the clinical applications of new medicines, therapeutic agents and diagnostics in cardiovascular disease. Coverage includes drug therapy, heart disease, vascular disorders, hypertension, cholesterol in cardiovascular disease, heart disease, stroke, heart failure and cardiovascular surgery. The Expert Review format is unique. Each review provides a complete overview of current thinking in a key area of research or clinical practice.