Mohamed Elsaid , Majd H. Alkhawaldeh , Mariam Abdelrauf Mahmoud , Ahmed Moumen , Moustafa Salem , Mohamed Fouad Abdrabo , Saad Abuzahra , Mohammed Ahmed Sadeq , Mohamed Hady Ashry , Abdelrahman Yousry Afify
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引用次数: 0
Abstract
Introduction
It is not uncommon for patients having PCI/angiography to encounter hemodynamic instability and psychological anxiety. The potential of aromatherapy as a supplementary intervention to mitigate these sensations and decrease perioperative complications has been the subject of several research.
Objectives
The study aims to evaluate the efficacy of aromatherapy in patients who underwent PCI/angiography.
Methods
A thorough search was carried out up to February 2023 across seven electronic databases (PubMed, Cochrane Library, Scopus, clinicaltrials, CINAHL, Embase, and WHO ICTRP) in order to find pertinent research. Included were RCTs looking into how aromatherapy affected PCI/angiography patients. Anxiety, blood pressure, heart rate, respiration, pain, and sleep quality were among the outcome measurements that were collected and analyzed. We performed the meta-analysis using “meta” package in R studio (V4.1.3) employing the random effects model when heterogeneity is significant (I2 > 50 % or p < 0.05) Additionally, the risk of bias was assessed using the revised Cochrane risk of bias tool (RoB2).
Results
Five RCTs enrolling 449 patients were included. Aromatherapy demonstrated a statistically significant reduction in anxiety (SMD = −0.56; 95 % CI [-0.98; −0.14], p < 0.01, [I2 = 66 %, p = 0.05]), heart rate (SMD= −0.42, 95 % CI [ −0.68; −0.17], p < 0.01), Systolic and diastolic blood Pressure (SMD = −0.29; 95 %CI [-0.49; −0.10], p < 0.01, [I2 = 33 %, p = 0.20]), (SMD = −0.22; 95 % CI [-0.41; −0.03], p = 0.03, [I2 = 0 %, p = 0.54]). respectively. Furthermore, inhalation aromatherapy was reportedly associated with a significant decrease in pain score compared to control in two different studies (p < 0.05). However, there was no statistically significant change in pooled respiratory rate (p > 0.05). Regarding the risk of bias, three studies showed low risk while only one showed high risk of bias.
Conclusion
Aromatherapy significantly improved anxiety, heart rate, SBP and DBP in patients underwent PCI/angiography. However, these results should be interpreted cautiously due to absence of blindness in such studies, moreover, heterogeneity of aromatherapy methods has been reported. Therefore, further RCTs are recommended to compare those methods, determine the optimal dosage, duration of treatment and to evaluate the long-term effects and safety profile of aromatherapy.
期刊介绍:
Advances in Integrative Medicine (AIMED) is an international peer-reviewed, evidence-based research and review journal that is multi-disciplinary within the fields of Integrative and Complementary Medicine. The journal focuses on rigorous quantitative and qualitative research including systematic reviews, clinical trials and surveys, whilst also welcoming medical hypotheses and clinically-relevant articles and case studies disclosing practical learning tools for the consulting practitioner. By promoting research and practice excellence in the field, and cross collaboration between relevant practitioner groups and associations, the journal aims to advance the practice of IM, identify areas for future research, and improve patient health outcomes. International networking is encouraged through clinical innovation, the establishment of best practice and by providing opportunities for cooperation between organisations and communities.