Direct and indirect experiences, risk perceptions, and vaccine booster intention: A mediation study in Singapore using secondary risk theory

IF 4.5 3区 医学 Q2 IMMUNOLOGY
Sonny Rosenthal , Agnes S.F. Chuah , Hye Kyung Kim , Shirley S. Ho
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Abstract

This study examined how direct experiences with COVID-19 infection and vaccination and indirect experience through government and media information predict individuals' intention to receive a COVID-19 booster dose. Drawing on secondary risk theory, we conducted a nationally representative door-to-door survey of 1000 adult Singapore residents in mid-2024. We used structural equation modeling to test whether risk perceptions and efficacy beliefs mediate the effects of experience and information exposure on booster intention. Booster intention was positively related to perceived susceptibility to infection, vaccine effectiveness, vaccination self-efficacy, and prior vaccination, and negatively related to perceived severity of and susceptibility to booster side effects and prior COVID-19 infection. The model explained 26 % of the variance in booster intention. Prior infection positively predicted perceived susceptibility to infection and negatively predicted perceived vaccine effectiveness. Prior vaccination positively predicted perceived vaccine effectiveness and self-efficacy, and negatively predicted concerns about side effects. Information exposure via the government and television news was positively related to perceived severity of and susceptibility to illness and vaccination self-efficacy. There were three notable mediation effects in the prediction of booster intention. The effect of prior infection was mediated by perceived vaccine effectiveness and the effect of prior vaccination was mediated by perceived vaccine effectiveness and perceived severity of vaccine side effects. These findings suggest that personal vaccination history and beliefs about vaccine effectiveness and safety may be especially important for promoting booster uptake.
直接和间接经验、风险感知和疫苗增强者意向:新加坡使用二次风险理论的中介研究
本研究考察了COVID-19感染和疫苗接种的直接经历以及通过政府和媒体信息获得的间接经历如何预测个人接受COVID-19加强剂的意愿。根据二次风险理论,我们在2024年中期对1000名新加坡成年居民进行了全国代表性的挨家挨户调查。我们使用结构方程模型来检验风险感知和功效信念是否介导经验和信息暴露对助推器意向的影响。接种意愿与感知感染易感性、疫苗有效性、疫苗接种自我效能、既往接种呈正相关,与感知增强剂副作用严重程度、易感性、既往COVID-19感染负相关。该模型解释了26%的助推器意向差异。既往感染正向预测感知感染易感性,负向预测感知疫苗有效性。先前接种疫苗对疫苗有效性和自我效能感有正向预测,对副作用的担忧有负向预测。通过政府和电视新闻的信息暴露与疾病严重程度、易感性和疫苗接种自我效能感呈正相关。助推器意向的预测存在三个显著的中介效应。既往感染的影响由疫苗有效性感知介导,既往接种疫苗的影响由疫苗有效性感知和疫苗副作用严重程度感知介导。这些发现表明,个人的疫苗接种史和对疫苗有效性和安全性的信念可能对促进加强接种尤其重要。
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来源期刊
Vaccine
Vaccine 医学-免疫学
CiteScore
8.70
自引率
5.50%
发文量
992
审稿时长
131 days
期刊介绍: Vaccine is unique in publishing the highest quality science across all disciplines relevant to the field of vaccinology - all original article submissions across basic and clinical research, vaccine manufacturing, history, public policy, behavioral science and ethics, social sciences, safety, and many other related areas are welcomed. The submission categories as given in the Guide for Authors indicate where we receive the most papers. Papers outside these major areas are also welcome and authors are encouraged to contact us with specific questions.
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