Application of microneedle patch in food and medical analysis

IF 11.8 1区化学 Q1 CHEMISTRY, ANALYTICAL

Trends in Analytical Chemistry Pub Date : 2025-06-20 DOI:10.1016/j.trac.2025.118351

Hui Jiang , Qing Tang , Donglei Jiang , Xinmei Liu , Wei Shen , Qiushi Feng , Bin Di , Jun Yang

{"title":"Application of microneedle patch in food and medical analysis","authors":"Hui Jiang , Qing Tang , Donglei Jiang , Xinmei Liu , Wei Shen , Qiushi Feng , Bin Di , Jun Yang","doi":"10.1016/j.trac.2025.118351","DOIUrl":null,"url":null,"abstract":"<div><div>Microneedle patch is a research hotspot in recent years. It refers to a patch material composed of microscale needle-like protrusions arranged in an array and is available as solid patch, hollow patch, hydrogel patch, porous patch, etc. It offers the strong points of relatively little dimensions, minimal invasiveness, portability and low cost. It has already been commercially applied in the fields of drug and cosmetics delivery. As a sampling technology, microneedle patch has also been applied in food analysis, drug monitoring, and disease monitoring. The microneedle patch can be integrated with sensors, such as flexible electronics, biochemical sensors, and soft microfluidics. The classification, preparation methods, extraction principles, and integration approaches of microneedle patch with biosensors as well as microfluidic devices in food and medicine were introduced in this paper. Finally, the development prospects of microneedle patch in the field of sample collection were discussed.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"191 ","pages":"Article 118351"},"PeriodicalIF":11.8000,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Analytical Chemistry","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165993625002195","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}

引用次数: 0

Abstract

Microneedle patch is a research hotspot in recent years. It refers to a patch material composed of microscale needle-like protrusions arranged in an array and is available as solid patch, hollow patch, hydrogel patch, porous patch, etc. It offers the strong points of relatively little dimensions, minimal invasiveness, portability and low cost. It has already been commercially applied in the fields of drug and cosmetics delivery. As a sampling technology, microneedle patch has also been applied in food analysis, drug monitoring, and disease monitoring. The microneedle patch can be integrated with sensors, such as flexible electronics, biochemical sensors, and soft microfluidics. The classification, preparation methods, extraction principles, and integration approaches of microneedle patch with biosensors as well as microfluidic devices in food and medicine were introduced in this paper. Finally, the development prospects of microneedle patch in the field of sample collection were discussed.

查看原文本刊更多论文

微针贴片在食品和医学分析中的应用

微针贴片是近年来的研究热点。它是指由微尺度针状突起排列成阵列构成的贴片材料，有实心贴片、空心贴片、水凝胶贴片、多孔贴片等。它具有相对较小的尺寸、最小的侵入性、可移植性和低成本等优点。它已经在药物和化妆品输送领域得到了商业应用。微针贴片作为一种采样技术，在食品分析、药物监测、疾病监测等方面也有广泛的应用。微针贴片可以与传感器集成，如柔性电子、生化传感器和软微流体。本文介绍了微针贴片的分类、制备方法、提取原理以及与生物传感器和微流控器件在食品和医药领域的集成途径。最后对微针贴片在样品采集领域的发展前景进行了展望。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Trends in Analytical Chemistry 化学-分析化学

CiteScore

20.00

自引率

4.60%

发文量

257

审稿时长

3.4 months

期刊介绍： TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.