Cynthia Y. Tang, Alex D. Waldman, Lawrence F. Brass
{"title":"Training physician-scientists, a view from inside","authors":"Cynthia Y. Tang, Alex D. Waldman, Lawrence F. Brass","doi":"10.1038/s41591-025-03786-5","DOIUrl":null,"url":null,"abstract":"<p>Physician-scientists are essential for translating research into clinical practice, yet recent US policy changes, combined with a protracted training path, threaten the stability of the current workforce and the ability to train their successors. As physician-scientist trainees (C.Y.T. and A.D.W.) and a director of physician-scientist training (L.F.B.), we have seen the US investment in biomedical research rapidly shift from a shared public value to a source of division. Cuts to research funding risk stalling breakthrough discoveries, and the suspension of pipeline training programs raises barriers to entry<sup>1,2,3,4</sup>. In less than 6 weeks, over US$1.8 billion of National Institutes of Health (NIH) grant funding was terminated, and 20% of these grants were for training, fellowship, and career development awards<sup>5</sup>. Without urgent intervention, these abrupt policy shifts will compromise medical advances, drive away talented individuals, and move medical discoveries, new drug identification, and therapeutic advances overseas. Here, we examine barriers across the training continuum, concluding with a call to action.</p><p>Historically, federal funding supported crucial entry points for prospective physician-scientists. Competitive programs such as the NIH Summer Internship Program and the National Science Foundation (NSF) Research Experiences for Undergraduates offered early research exposure and mentorship. Suspending these programs disproportionately affects those who rely on structured pathways to enter physician-scientist training, weakening efforts to cultivate a biomedical workforce with diverse perspectives.</p>","PeriodicalId":19037,"journal":{"name":"Nature Medicine","volume":"16 1","pages":""},"PeriodicalIF":58.7000,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41591-025-03786-5","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Physician-scientists are essential for translating research into clinical practice, yet recent US policy changes, combined with a protracted training path, threaten the stability of the current workforce and the ability to train their successors. As physician-scientist trainees (C.Y.T. and A.D.W.) and a director of physician-scientist training (L.F.B.), we have seen the US investment in biomedical research rapidly shift from a shared public value to a source of division. Cuts to research funding risk stalling breakthrough discoveries, and the suspension of pipeline training programs raises barriers to entry1,2,3,4. In less than 6 weeks, over US$1.8 billion of National Institutes of Health (NIH) grant funding was terminated, and 20% of these grants were for training, fellowship, and career development awards5. Without urgent intervention, these abrupt policy shifts will compromise medical advances, drive away talented individuals, and move medical discoveries, new drug identification, and therapeutic advances overseas. Here, we examine barriers across the training continuum, concluding with a call to action.
Historically, federal funding supported crucial entry points for prospective physician-scientists. Competitive programs such as the NIH Summer Internship Program and the National Science Foundation (NSF) Research Experiences for Undergraduates offered early research exposure and mentorship. Suspending these programs disproportionately affects those who rely on structured pathways to enter physician-scientist training, weakening efforts to cultivate a biomedical workforce with diverse perspectives.
期刊介绍:
Nature Medicine is a monthly journal publishing original peer-reviewed research in all areas of medicine. The publication focuses on originality, timeliness, interdisciplinary interest, and the impact on improving human health. In addition to research articles, Nature Medicine also publishes commissioned content such as News, Reviews, and Perspectives. This content aims to provide context for the latest advances in translational and clinical research, reaching a wide audience of M.D. and Ph.D. readers. All editorial decisions for the journal are made by a team of full-time professional editors.
Nature Medicine consider all types of clinical research, including:
-Case-reports and small case series
-Clinical trials, whether phase 1, 2, 3 or 4
-Observational studies
-Meta-analyses
-Biomarker studies
-Public and global health studies
Nature Medicine is also committed to facilitating communication between translational and clinical researchers. As such, we consider “hybrid” studies with preclinical and translational findings reported alongside data from clinical studies.