Acute Kidney Injury in Endocrine Emergencies.

IF 2.1 4区 医学 Q2 PERIPHERAL VASCULAR DISEASE
Nadezda Petejova, Josef Zadrazil, David Karasek, Arnost Martinek, Vladimir Teplan, Marianna Bystrianska, Marcela Kanova
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Abstract

Background: Acute kidney injury (AKI) is a serious condition in clinical medicine that significantly increases morbidity and mortality, particularly in critically ill patients. Rapid and accurate identification of the underlying causes of AKI is crucial for determining appropriate therapeutic management and potentially saving the patient's life. Although endocrine emergencies are a less common cause of AKI in critically ill patients, recognizing when they occur is vital to comprehensive care.

Summary: AKI can impair the endocrine system and result in critical conditions for patients, particularly in cases of sepsis. In addition, several factors can contribute to severe conditions associated with AKI, including thyrotoxicosis, adrenal crisis, severe hypothyroidism, complications related to diabetes mellitus, panhypopituitarism, diabetes insipidus with acute hypernatremia, severe hypercalcemia, neuroendocrine tumors, and ovarian hyperstimulation syndrome.

Key message: The early recognition of endocrine emergencies and the impact of AKI on the endocrine system in critically ill patients is essential to intensive and comprehensive care.

内分泌急症中的急性肾损伤。
背景:急性肾损伤(AKI)是临床医学中一种严重的疾病,可显著增加发病率和死亡率,尤其是危重患者。快速准确地识别AKI的根本原因对于确定适当的治疗管理和可能挽救患者的生命至关重要。虽然内分泌急症是危重患者AKI的不常见原因,但认识到它们何时发生对全面护理至关重要。总结:AKI可损害内分泌系统并导致患者的危急情况,特别是在败血症的情况下。此外,有几个因素可导致AKI相关的严重疾病,包括甲状腺毒症、肾上腺危象、严重甲状腺功能减退、糖尿病相关并发症、全垂体功能低下、尿崩症合并急性高钠血症、严重高钙血症、神经内分泌肿瘤和卵巢过度刺激综合征。关键信息:早期识别内分泌紧急情况和AKI对危重患者内分泌系统的影响对于加强和全面护理至关重要。
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来源期刊
Kidney & blood pressure research
Kidney & blood pressure research 医学-泌尿学与肾脏学
CiteScore
4.80
自引率
3.60%
发文量
61
审稿时长
6-12 weeks
期刊介绍: This journal comprises both clinical and basic studies at the interface of nephrology, hypertension and cardiovascular research. The topics to be covered include the structural organization and biochemistry of the normal and diseased kidney, the molecular biology of transporters, the physiology and pathophysiology of glomerular filtration and tubular transport, endothelial and vascular smooth muscle cell function and blood pressure control, as well as water, electrolyte and mineral metabolism. Also discussed are the (patho)physiology and (patho) biochemistry of renal hormones, the molecular biology, genetics and clinical course of renal disease and hypertension, the renal elimination, action and clinical use of drugs, as well as dialysis and transplantation. Featuring peer-reviewed original papers, editorials translating basic science into patient-oriented research and disease, in depth reviews, and regular special topic sections, ''Kidney & Blood Pressure Research'' is an important source of information for researchers in nephrology and cardiovascular medicine.
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