{"title":"Utilization of apitherapy in a liposarcoma in a guinea pig","authors":"Samuel Batson, Joerg Mayer","doi":"10.1053/j.jepm.2025.05.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>The use of bee products such as bee venom and IV honey solution is an under-documented avenue of adjunctive therapy when treating neoplasms.</div></div><div><h3>Case description</h3><div>A 2-year-old female guinea pig presented with a recurrent submandibular liposarcoma. Administration of bee venom was utilized to prolong reoccurrence, and no growth was seen in the first 141 days. The mass eventually did recrudesce, and bee venom along with IV honey were employed over the following 120 days, where the tumor again eventually regressed in size. Within the next 100 days, the tumor regrew and apitherapy was once again initiated, where the mass fluctuated in size. The guinea pig eventually succumbed to secondary cardiopulmonary distress and was euthanized.</div></div><div><h3>Conclusions and case relevance</h3><div>Administration of bee venom at the site of the mass correlated with regression in tumor size on several occasions. The relevance of adjuvant apitherapy for its antineoplastic effects should be considered and further study is warranted due to its potential to impact treating otherwise challenging neoplastic disease.</div></div>","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"54 ","pages":"Pages 17-20"},"PeriodicalIF":0.5000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Exotic Pet Medicine","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1557506325000485","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Background
The use of bee products such as bee venom and IV honey solution is an under-documented avenue of adjunctive therapy when treating neoplasms.
Case description
A 2-year-old female guinea pig presented with a recurrent submandibular liposarcoma. Administration of bee venom was utilized to prolong reoccurrence, and no growth was seen in the first 141 days. The mass eventually did recrudesce, and bee venom along with IV honey were employed over the following 120 days, where the tumor again eventually regressed in size. Within the next 100 days, the tumor regrew and apitherapy was once again initiated, where the mass fluctuated in size. The guinea pig eventually succumbed to secondary cardiopulmonary distress and was euthanized.
Conclusions and case relevance
Administration of bee venom at the site of the mass correlated with regression in tumor size on several occasions. The relevance of adjuvant apitherapy for its antineoplastic effects should be considered and further study is warranted due to its potential to impact treating otherwise challenging neoplastic disease.
期刊介绍:
The Journal of Exotic Pet Medicine provides clinicians with a convenient, comprehensive, "must have" resource to enhance and elevate their expertise with exotic pet medicine. Each issue contains wide ranging peer-reviewed articles that cover many of the current and novel topics important to clinicians caring for exotic pets. Diagnostic challenges, consensus articles and selected review articles are also included to help keep veterinarians up to date on issues affecting their practice. In addition, the Journal of Exotic Pet Medicine serves as the official publication of both the Association of Exotic Mammal Veterinarians (AEMV) and the European Association of Avian Veterinarians (EAAV). The Journal of Exotic Pet Medicine is the most complete resource for practitioners who treat exotic pets.