Surface-enhanced Raman scattering detection of antibiotics

IF 11.8 1区化学 Q1 CHEMISTRY, ANALYTICAL

Trends in Analytical Chemistry Pub Date : 2025-06-22 DOI:10.1016/j.trac.2025.118352

Waqas Ahmad , Muhammad Zareef , Min Chen , Yi Xu , Jingjing Wang , Quansheng Chen

{"title":"Surface-enhanced Raman scattering detection of antibiotics","authors":"Waqas Ahmad , Muhammad Zareef , Min Chen , Yi Xu , Jingjing Wang , Quansheng Chen","doi":"10.1016/j.trac.2025.118352","DOIUrl":null,"url":null,"abstract":"<div><div>The extensive use of antibiotics has led to residues seeping into the food chain and water supplies, creating a hidden yet pervasive threat. To control antibiotic residues and prevent the silent spread of resistance, it is essential to use modern technologies for their detection. Surface-enhanced Raman scattering (SERS)-based detection offers molecular fingerprint signatures enabling differentiation among structurally related antibiotics. Thus, the current review oversees an up-to-date coverage of the advances in SERS-antibiotics detection in foodstuffs, water, and biological matrices. The study systematically <strong>(i)</strong> categorizes all groups of antibiotics (quinolones, tetracyclines, sulfonamides, aminoglycoside, amphenicols, β-lactams, nitrofuran, macrolides and nitroimidazoles); <strong>(ii)</strong> evaluates nanosubstrate design, novelty, detection (label/label-free) modes, experimental bands assignment, mechanism, orientation on the substrate, and other routine SERS metrics; and finally <strong>(iii)</strong> highlight limitations and future trends in antibiotic-SERS detection. The review will be applicable in diverse fields of chemical (bio)sensors, analytical chemistry, materials science, food science, and environmental monitoring.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"191 ","pages":"Article 118352"},"PeriodicalIF":11.8000,"publicationDate":"2025-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Analytical Chemistry","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165993625002201","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}

引用次数: 0

Abstract

The extensive use of antibiotics has led to residues seeping into the food chain and water supplies, creating a hidden yet pervasive threat. To control antibiotic residues and prevent the silent spread of resistance, it is essential to use modern technologies for their detection. Surface-enhanced Raman scattering (SERS)-based detection offers molecular fingerprint signatures enabling differentiation among structurally related antibiotics. Thus, the current review oversees an up-to-date coverage of the advances in SERS-antibiotics detection in foodstuffs, water, and biological matrices. The study systematically (i) categorizes all groups of antibiotics (quinolones, tetracyclines, sulfonamides, aminoglycoside, amphenicols, β-lactams, nitrofuran, macrolides and nitroimidazoles); (ii) evaluates nanosubstrate design, novelty, detection (label/label-free) modes, experimental bands assignment, mechanism, orientation on the substrate, and other routine SERS metrics; and finally (iii) highlight limitations and future trends in antibiotic-SERS detection. The review will be applicable in diverse fields of chemical (bio)sensors, analytical chemistry, materials science, food science, and environmental monitoring.

查看原文本刊更多论文

表面增强拉曼散射检测抗生素

抗生素的广泛使用导致其残留物渗入食物链和供水系统，造成了一个隐藏但普遍存在的威胁。为了控制抗生素残留和防止耐药性的无声传播，必须使用现代技术进行检测。基于表面增强拉曼散射（SERS）的检测提供了分子指纹特征，可以区分结构相关的抗生素。因此，本综述对食品、水和生物基质中sers -抗生素检测的最新进展进行了监督。该研究系统地(i)对所有类别的抗生素（喹诺酮类、四环素类、磺胺类、氨基糖苷类、氨霉素类、β-内酰胺类、硝基呋喃类、大环内酯类和硝基咪唑类）进行了分类；（ii）评估纳米衬底设计、新颖性、检测（标签/无标签）模式、实验波段分配、机制、衬底上的方向和其他常规SERS指标；最后（iii）强调抗生素- sers检测的局限性和未来趋势。该综述将适用于化学（生物）传感器、分析化学、材料科学、食品科学和环境监测等各个领域。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Trends in Analytical Chemistry 化学-分析化学

CiteScore

20.00

自引率

4.60%

发文量

257

审稿时长

3.4 months

期刊介绍： TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.