Subcutaneous Fat Area Can Be as a Predictors of Drainage Volume After Lobectomy for Lung Cancer.

IF 2.3 3区医学 Q3 ONCOLOGY

Thoracic Cancer Pub Date : 2025-06-01 DOI:10.1111/1759-7714.70114

Jie Xu, Shuai Yuan, Xiaopeng An, Jie Dong

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引用次数: 0

Abstract

Objective: Currently, no uniform standard exists for the maximum drainage volume permitting chest tube removal following lobectomy in lung cancer patients, and limited research has explored factors influencing postoperative drainage. This study aimed to investigate the relationship between subcutaneous fat area (SFA) and postoperative drainage volume.

Methods: We conducted a retrospective analysis of 509 lung cancer patients who underwent video-assisted thoracoscopic lobectomy. Clinical characteristics, postoperative outcomes (length of stay, hospitalization expenses), blood parameters, chest tube duration, 3-day postoperative drainage volume, and SFA were recorded. Predictive factors for drainage volume were identified using univariate and multivariate logistic regression analyses. SFA was measured at the level of the 12th thoracic vertebra cross-section using preoperative CT imaging.

Results: The analysis revealed significant positive correlations between chest tube duration and both length of stay (p < 0.001) and hospitalization expenses (p < 0.001). Chest tube duration (< 3 vs. ≥ 3 days) was primarily determined by 3-day postoperative drainage volume (574 ± 252 vs. 885 ± 362 mL; p < 0.001). Univariate analysis demonstrated that 3-day postoperative drainage volume correlated with age (p < 0.001), gender (p = 0.002), pathological type (p < 0.001), diabetes (p = 0.026), hypertension (p = 0.011), and SFA (p < 0.001). Multivariate logistic regression confirmed that age ≥ 65 years (p = 0.016), small cell lung cancer (SCLC; p = 0.022), and SFA ≥ 100 cm² (p = 0.005) were independently associated with postoperative drainage volume ≥ 650 mL.

Conclusions: SFA significantly correlated with 3-day postoperative drainage volume and may serve as a predictor for drainage volume following lobectomy in lung cancer patients. This association highlights its utility in guiding chest tube removal timing and potentially reducing the risk of pleural effusion recurrence.

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皮下脂肪面积可作为肺癌肺叶切除术后引流量的预测指标。

目的：目前，对于肺癌患者肺叶切除术后切除胸管的最大引流量没有统一的标准，对影响术后引流量的因素研究有限。本研究旨在探讨皮下脂肪面积（SFA）与术后引流量的关系。方法：我们对509例接受电视胸腔镜肺叶切除术的肺癌患者进行回顾性分析。记录两组患者的临床特征、术后结局（住院时间、住院费用）、血液参数、胸管时间、术后3 d引流量、SFA。采用单因素和多因素logistic回归分析确定引流量的预测因素。术前CT成像在第12胸椎横切面水平测量SFA。结果：分析显示胸管持续时间与住院时间呈正相关（p 2 (p = 0.005)），且与术后引流量≥650 mL独立相关。结论：SFA与术后3天引流量显著相关，可作为肺癌患者肺叶切除术后引流量的预测指标。这一关联突出了其在指导胸管拔出时机和潜在降低胸腔积液复发风险方面的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Thoracic Cancer ONCOLOGY-RESPIRATORY SYSTEM

CiteScore

5.20

自引率

3.40%

发文量

439

审稿时长

2 months

期刊介绍： Thoracic Cancer aims to facilitate international collaboration and exchange of comprehensive and cutting-edge information on basic, translational, and applied clinical research in lung cancer, esophageal cancer, mediastinal cancer, breast cancer and other thoracic malignancies. Prevention, treatment and research relevant to Asia-Pacific is a focus area, but submissions from all regions are welcomed. The editors encourage contributions relevant to prevention, general thoracic surgery, medical oncology, radiology, radiation medicine, pathology, basic cancer research, as well as epidemiological and translational studies in thoracic cancer. Thoracic Cancer is the official publication of the Chinese Society of Lung Cancer, International Chinese Society of Thoracic Surgery and is endorsed by the Korean Association for the Study of Lung Cancer and the Hong Kong Cancer Therapy Society. The Journal publishes a range of article types including: Editorials, Invited Reviews, Mini Reviews, Original Articles, Clinical Guidelines, Technological Notes, Imaging in thoracic cancer, Meeting Reports, Case Reports, Letters to the Editor, Commentaries, and Brief Reports.