Clinical Presentation and Diagnosis of Multisystemic Eosinophilic Epitheliotropic Disease in a Miniature Donkey: A Case Report

Abstract

A 21-year-old miniature donkey gelding was evaluated for pruritus, inappetence, hypertriglyceridemia, and alopecia of 2 weeks' duration. Hematology showed moderate eosinophilia, severe hypertriglyceridemia, and moderately increased liver enzyme activities. Cytologic evaluation of peritoneal fluid identified an eosinophilic transudate. The donkey was treated with antihistamines, anthelmintics, IV fluids with dextrose as a constant rate infusion, and insulin. The miniature donkey was euthanized because of the development of laminitis. Lesions associated with multisystemic eosinophilic epitheliotropic disease (MEED) were identified at necropsy.