Multianalyte Nanopore Detection of Alzheimer's Disease Biomarkers: A Label-Free Platform with Improved Sensitivity and Range (Adv. Healthcare Mater. 16/2025)
Qianshan Liu, Yulin Ouyang, Yunjiao Wang, Shuo Zhou, Yang Zhan, Liang Wang
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引用次数: 0
Abstract
Alzheimer's Biomarkers
In article 2405058, Yang Zhan, Liang Wang, and co-workers describe recent advances in multianalyte nanopore detection of Alzheimer's biomarkers: a label-free platform with improved sensitivity and range. The image shows a little boy wearing a headlight, holding a net filled with tadpoles at dawn—a metaphor for how nanopore technology can detect and distinguish various Alzheimer's disease-related pathological proteins in bodily fluids during early stages. The mountain peaks in the background represent the current blockade amplitudes generated as different protein biomarkers pass through the nanopore.
在文章2405058中,Zhan Yang, Wang Liang及其同事描述了多分析物纳米孔检测阿尔茨海默病生物标志物的最新进展:一种提高灵敏度和范围的无标记平台。这张图片显示了一个小男孩戴着头灯,在黎明时分拿着一个装满蝌蚪的网——这是一个比喻,纳米孔技术如何在早期阶段检测和区分体液中与阿尔茨海默病相关的各种病理蛋白质。背景中的山峰表示不同蛋白质生物标志物通过纳米孔时产生的电流阻断幅度。
期刊介绍:
Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.