Back Cover: Size-dependent Stability and Luminescence Property in Organic Aggregates

IF 13.9 Q1 CHEMISTRY, MULTIDISCIPLINARY

Aggregate (Hoboken, N.J.) Pub Date : 2025-06-22 DOI:10.1002/agt2.70082

Junfang Yang, Jikai Lv, Yuan Jiao, Xiaoyan Zheng, Qian Peng

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Abstract

This work explores the critical sizes of stable aggregates and their bright luminescence for helical hexaphenylsilole and planar 3-(2-cyano-2-phenylethenyl-Z)-NH-indole aggregation-induced emission luminogens, providing dynamic insights into the aggregation-induced emission (AIE) mechanism and invaluable guidance for optimizing the size of AIE-based nanoparticles in practical bioimaging and sensing applications (e70029). This review highlights cutting-edge strategies for enhancing the detection of pathogen-derived extracellular vesicles, including novel aggregate materials and machine learning approaches. Pathogen-derived vesicles are pivotal in host-pathogen interactions and possess significant diagnostic promise, as their unique cargo offers a rich repository of potential biomarkers. Enhancing vesicle detection may ultimately pave the way for transformative clinical applications (e70018).

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封底：有机聚集体的尺寸依赖性稳定性和发光特性

本研究探索了螺旋六苯基硅和平面3-(2-氰基-2-苯基- z)- nh -吲哚聚集诱导发射发光物质的稳定聚集体的临界尺寸及其明亮发光，为聚集诱导发射（AIE）机制提供了动态见解，并为优化AIE纳米颗粒在实际生物成像和传感应用中的尺寸提供了宝贵的指导（e70029）。本文综述了加强病原体来源的细胞外囊泡检测的前沿策略，包括新型聚集体材料和机器学习方法。病原体来源的囊泡在宿主-病原体相互作用中起着关键作用，并且具有重要的诊断前景，因为它们独特的货物提供了丰富的潜在生物标志物库。增强囊泡检测可能最终为变革性临床应用铺平道路（e70018）。

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