Intraoperative ICG-VA with FLOW800 and multimodal fusion neuro-navigation for the resection of arteriovenous malformation with reduced blood loss.

Abstract

Objective: To assess the safety and effectiveness of combining indocyanine green videoangiography (ICG-VA) with FLOW800 and multimodal fusion neuro-navigation in brain arteriovenous malformation microsurgical resection.

Methods: From January 1, 2019, to December 31, 2022, 90 consecutive patients at The First Affiliated Hospital of Soochow University diagnosed with AVMs were included. Patients were divided into a combined treatment group and a non-combined treatment group based on the treatment received. Clinical data including baseline characteristics, image findings, mRS, pre- and postoperation hemoglobin/ hematocrit levels were reviewed and collected for statistical analysis.

Results: Compared with the non-combined treatment group, the combined treatment group demonstrated a smaller postoperative decline in hemoglobin and hematocrit levels after operation, as well as a higher proportion of patients with no disability at discharge and at the six-month follow-up. Additionally, the combined treatment group had lower rates of reoperation and post-operative complications. Compared with the non-combined-treatment group, the combined-treatment group demonstrated a smaller postoperative decline in hemoglobin and hematocrit levels, as well as a higher proportion of patients with no disability at discharge and at the six-month follow-up. Additionally, the combined-treatment group had lower rates of reoperation and postoperative complications.

Conclusions: The combined utilization of intraoperative ICG-VA with FLOW800 and multimodal fusion neuro-navigation appears to reduce intraoperative blood loss and enhance functional outcomes in AVM microsurgery, thereby improving both the safety and efficacy of the procedure.