Davide Marotta, Noor Ward, Steven R Bauer, Joshua Hunsberger, Jana Stoudemire, Kenneth Savin, Marc Giulianotti, Catriona H M Jamieson, Donna Roberts, Michael Roberts
{"title":"Biomanufacturing in low Earth orbit: A paradigm shift.","authors":"Davide Marotta, Noor Ward, Steven R Bauer, Joshua Hunsberger, Jana Stoudemire, Kenneth Savin, Marc Giulianotti, Catriona H M Jamieson, Donna Roberts, Michael Roberts","doi":"10.1016/j.stemcr.2025.102536","DOIUrl":null,"url":null,"abstract":"<p><p>This perspective article explores the transformative potential of biomanufacturing in low Earth orbit (LEO) for regenerative medicine. Building on key symposia and workshops, it highlights the International Space Station (ISS) National Laboratory's role in advancing tissue engineering through microgravity research. The article discusses breakthroughs in stem cell therapies, disease modeling, and automation, while emphasizing the need for collaboration, investment, and emerging technologies like AI and machine learning. Insights from the scientific community and market analyses point to a rapidly growing sector. Strategic partnerships and policy support will be essential to scale space-based biomanufacturing and unlock new therapeutic possibilities for patients on Earth.</p>","PeriodicalId":21885,"journal":{"name":"Stem Cell Reports","volume":" ","pages":"102536"},"PeriodicalIF":5.9000,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12277831/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Stem Cell Reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.stemcr.2025.102536","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/19 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CELL & TISSUE ENGINEERING","Score":null,"Total":0}
引用次数: 0
Abstract
This perspective article explores the transformative potential of biomanufacturing in low Earth orbit (LEO) for regenerative medicine. Building on key symposia and workshops, it highlights the International Space Station (ISS) National Laboratory's role in advancing tissue engineering through microgravity research. The article discusses breakthroughs in stem cell therapies, disease modeling, and automation, while emphasizing the need for collaboration, investment, and emerging technologies like AI and machine learning. Insights from the scientific community and market analyses point to a rapidly growing sector. Strategic partnerships and policy support will be essential to scale space-based biomanufacturing and unlock new therapeutic possibilities for patients on Earth.
期刊介绍：
Stem Cell Reports publishes high-quality, peer-reviewed research presenting conceptual or practical advances across the breadth of stem cell research and its applications to medicine. Our particular focus on shorter, single-point articles, timely publication, strong editorial decision-making and scientific input by leaders in the field and a "scoop protection" mechanism are reasons to submit your best papers.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
