The structure of posttraumatic stress symptoms in youth with and without obsessive-compulsive disorder: New insights using factor and network analysis

Caitlin M. Pinciotti , Matti Cervin , Kendall N. Drummond , Jeffrey D. Shahidullah , Justin F. Rousseau , Cody G. Dodd , Mercedes Ramirez , John M. Hettema , Robyn Richmond , Leslie K. Taylor , Lynn Monnat , Leslie Proch , Fei Teng , Wayne K. Goodman , Eric A. Storch , Andrew G. Guzick , D. Jeffrey Newport , Karen Dineen Wagner , Charles B. Nemeroff
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Abstract

Posttraumatic stress disorder (PTSD) and obsessive-compulsive disorder (OCD) share ostensibly similar and sometimes overlapping symptoms that complicate diagnostic assessment and conceptualization. While varying models for the symptom structure of PTSD have been proposed – including the presently used 4-factor and a more fine-grained 7-factor model – little research has focused on youth and even less is known about how these symptoms relate to one another when OCD is present. The present study used confirmatory factor analysis (CFA) and network analysis to compare PTSD symptom relations among 2066 trauma-exposed youth aged 8–20 enrolled in the Texas Childhood Trauma Research Network, of which 10.9 % met diagnostic criteria for OCD. CFA model fit was strongest for the 7-factor PTSD model, and multigroup CFA found no evidence that the structure differed as a function of OCD diagnosis, sex, nor age group. Internal consistency in the 7-factor model ranged from poor to good (α = 0.59–0.80), while all clusters of the 4-factor model demonstrated adequate internal consistency (α = 0.75–0.89). Network analysis revealed unique associations between PTSD and OCD. Specifically, having OCD was linked to more Negative Affect (edge = 0.15) and Anhedonia (edge = 0.16), which are both part of the 4-factor Negative Alterations in Cognitions and Mood symptom cluster. While the clinical relevance of the 7-factor model is still unclear, it evidenced mixed empirical support in the present sample and provided greater nuance when examining links between PTSD and OCD.
有和没有强迫症的青少年创伤后应激症状的结构:使用因素和网络分析的新见解
创伤后应激障碍(PTSD)和强迫症(OCD)表面上相似,有时重叠的症状使诊断评估和概念化复杂化。虽然人们提出了各种各样的PTSD症状结构模型——包括目前使用的4因素模型和更精细的7因素模型——但很少有研究关注年轻人,而当出现强迫症时,这些症状之间的关系就更少了。本研究采用验证性因子分析(CFA)和网络分析比较了2066名8-20岁的创伤暴露青年在德克萨斯儿童创伤研究网络中的PTSD症状关系,其中10.9 %符合强迫症的诊断标准。CFA模型对7因素PTSD模型拟合最强,多组CFA没有发现证据表明该结构随强迫症诊断、性别或年龄组的变化而不同。7因素模型的内部一致性从差到好(α = 0.59 ~ 0.80),而4因素模型的所有聚类的内部一致性都很好(α = 0.75 ~ 0.89)。网络分析揭示了创伤后应激障碍和强迫症之间的独特联系。具体来说,患有强迫症与更多的负面情绪(edge = 0.15)和快感缺乏(edge = 0.16)有关,这两者都是认知和情绪症状群中4因素负面改变的一部分。虽然7因素模型的临床相关性尚不清楚,但它在目前的样本中证明了混合的经验支持,并在研究PTSD和强迫症之间的联系时提供了更细微的差别。
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来源期刊
Journal of mood and anxiety disorders
Journal of mood and anxiety disorders Applied Psychology, Experimental and Cognitive Psychology, Clinical Psychology, Psychiatry and Mental Health, Psychology (General), Behavioral Neuroscience
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