Intermittent flow paths in biofilms grown in a microfluidic channel

IF 4 2区环境科学与生态学 Q1 WATER RESOURCES

Advances in Water Resources Pub Date : 2025-06-19 DOI:10.1016/j.advwatres.2025.105018

Kerem Bozkurt, Christoph Lohrmann, Felix Weinhardt, Daniel Hanke, Raphael Hopp, Robin Gerlach, Christian Holm, Holger Class

引用次数: 0

Abstract

Biofilms exposed to flow experience shear stress, which leads to a competitive interaction between the growth and development of a biofilm and shearing. In this study, Pseudonomas fluorescene biofilm was grown in a microfluidic channel and exposed to forced flow of an aqueous solution of variable velocity. It can be observed that under certain conditions preferential flow paths form with a dynamic, but quasi-steady state interaction of growth, detachment, and re-attachment. We find that the regimes for preferential flow path development are determined by nutrient availability and the ratio of shear stress versus the biofilm’s ability to resist shear forces. The intermittent regime of flow paths is mainly driven by the supply with nutrients, which we confirm by comparison with a numerical model based on coarse-grained molecular dynamics and Lattice Boltzmann hydrodynamics.

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微流体通道中生长的生物膜的间歇流动路径

暴露于流动中的生物膜经历剪切应力，这导致生物膜的生长和发育与剪切之间的竞争性相互作用。在本研究中，荧光假单胞菌生物膜在微流体通道中生长，并暴露于变速水溶液的强制流动中。可以观察到，在一定条件下，优先流动路径的形成是一种动态的、准稳态的生长、分离和再附着相互作用。我们发现优先流动路径发展的机制是由营养物质的可用性和剪切应力与生物膜抵抗剪切力的能力之比决定的。通过与基于粗粒度分子动力学和晶格玻尔兹曼流体动力学的数值模型的比较，我们证实了流动路径的间歇状态主要是由营养物质的供应驱动的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advances in Water Resources 环境科学-水资源

CiteScore

9.40

自引率

6.40%

发文量

171

审稿时长

36 days

期刊介绍： Advances in Water Resources provides a forum for the presentation of fundamental scientific advances in the understanding of water resources systems. The scope of Advances in Water Resources includes any combination of theoretical, computational, and experimental approaches used to advance fundamental understanding of surface or subsurface water resources systems or the interaction of these systems with the atmosphere, geosphere, biosphere, and human societies. Manuscripts involving case studies that do not attempt to reach broader conclusions, research on engineering design, applied hydraulics, or water quality and treatment, as well as applications of existing knowledge that do not advance fundamental understanding of hydrological processes, are not appropriate for Advances in Water Resources. Examples of appropriate topical areas that will be considered include the following: • Surface and subsurface hydrology • Hydrometeorology • Environmental fluid dynamics • Ecohydrology and ecohydrodynamics • Multiphase transport phenomena in porous media • Fluid flow and species transport and reaction processes