Levofloxacin-Induced Generalized Fixed Drug Eruption.

IF 1 Q3 MEDICINE, GENERAL & INTERNAL
Cureus Pub Date : 2025-06-19 eCollection Date: 2025-06-01 DOI:10.7759/cureus.86372
Hiebda Sofía Martínez Jiménez
{"title":"Levofloxacin-Induced Generalized Fixed Drug Eruption.","authors":"Hiebda Sofía Martínez Jiménez","doi":"10.7759/cureus.86372","DOIUrl":null,"url":null,"abstract":"<p><p>Fixed drug eruption (FDE) is a type of toxicodermatitis induced by a delayed hypersensitivity reaction (type IV) characterized by the reappearance of erythematous-violaceous plaques at the same site upon reexposure to the triggering agent. We present the case of a 72-year-old female who developed a generalized FDE following the administration of levofloxacin. Diagnosis was established clinically and supported by the Naranjo algorithm. The condition improved upon drug discontinuation. This case highlights the importance of recognizing less common presentations, such as generalized FDE, and the need for continued awareness among healthcare providers, especially given the frequent use of antibiotics like levofloxacin.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 6","pages":"e86372"},"PeriodicalIF":1.0000,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178587/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cureus","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7759/cureus.86372","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0

Abstract

Fixed drug eruption (FDE) is a type of toxicodermatitis induced by a delayed hypersensitivity reaction (type IV) characterized by the reappearance of erythematous-violaceous plaques at the same site upon reexposure to the triggering agent. We present the case of a 72-year-old female who developed a generalized FDE following the administration of levofloxacin. Diagnosis was established clinically and supported by the Naranjo algorithm. The condition improved upon drug discontinuation. This case highlights the importance of recognizing less common presentations, such as generalized FDE, and the need for continued awareness among healthcare providers, especially given the frequent use of antibiotics like levofloxacin.

左氧氟沙星致全身固定药疹。
固定药疹(FDE)是一种由迟发性超敏反应(IV型)引起的毒性皮炎,其特征是在再次暴露于触发剂后同一部位再次出现红斑-紫色斑块。我们提出的情况下,72岁的女性谁发展了广泛性FDE后,左氧氟沙星的管理。诊断建立在临床,并由Naranjo算法支持。停药后病情好转。本病例强调了认识不太常见的表现(如全面性FDE)的重要性,以及卫生保健提供者持续认识的必要性,特别是考虑到左氧氟沙星等抗生素的频繁使用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信