Cognitive and Affective Performance of Brazilian Long COVID Patients: An In-Depth Analysis Before and After Psychoeducational Rehabilitation.

IF 1.8 4区医学 Q3 CLINICAL NEUROLOGY

NeuroRehabilitation Pub Date : 2025-06-01 Epub Date: 2025-03-28 DOI:10.1177/10538135251327122

Lígia Maria do Nascimento Souza, George P Prigatano, Sandro Barbosa de Oliveira, Lucia Willadino Braga

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引用次数: 0

Abstract

BackgroundLong COVID patients report various cognitive and affective symptoms that are poorly understood.ObjectiveThis study analyzed cognitive and affective performance in 208 Long COVID patients pre and post psychoeducational rehabilitation using a standardized screening test of higher cerebral functions. Identifying persistent difficulties may help guide future rehabilitation efforts.MethodsThe sample was comprised by a subset of 208 who completed psychoeducational rehabilitation from 614 Long COVID patients seeking rehabilitation. Performance on specific items was analyzed and compared to a reference sample of 114 educationally matched normal functioning adults.ResultsDetailed item analyses in 208 patients revealed persistent difficulties in the efficiency of learning and memory, affective expression, and the ability to accurately predict verbal memory performance compared to a reference sample. Long COVID patients showed variable performance deficits on attention, visual-spatial problem solving and memory measures. Language and related functions were consistently at a level commensurate with normally functioning individuals.ConclusionsPersistent cognitive and affective impairments were identified in Long COVID patients post-rehabilitation. Future programs should aim on to improve the efficiency of learning and memory, enhance the range of affective expression, and improve self-awareness of functional capacities. Rehabilitation should consider the multifactorial causes of these neuropsychological symptoms.

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巴西长冠肺炎患者认知和情感表现：心理教育康复前后的深入分析

新冠肺炎患者报告了各种认知和情感症状，但人们对这些症状知之甚少。目的采用标准化的高等脑功能筛查测试，分析208例长冠肺炎患者心理教育康复前后的认知和情感表现。确定持续存在的困难可能有助于指导未来的康复工作。方法样本由614例寻求康复的长冠状病毒患者中完成心理教育康复的208人组成。对具体项目的表现进行了分析，并与114名教育程度相匹配的正常成年人的参考样本进行了比较。结果对208例患者的详细项目分析显示，与参考样本相比，他们在学习和记忆效率、情感表达以及准确预测言语记忆表现的能力方面存在持续困难。长期COVID患者在注意力、视觉空间问题解决和记忆测量方面表现出不同的表现缺陷。语言和相关功能始终处于与正常功能个体相称的水平。结论长冠肺炎患者康复后存在持续的认知和情感障碍。未来的计划应着眼于提高学习和记忆的效率，增强情感表达的范围，并提高自我意识的功能能力。康复治疗应考虑这些神经心理症状的多因素原因。

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来源期刊

NeuroRehabilitation CLINICAL NEUROLOGY-REHABILITATION

CiteScore

3.20

自引率

0.00%

发文量

178

审稿时长

6-12 weeks

期刊介绍： NeuroRehabilitation, an international, interdisciplinary, peer-reviewed journal, publishes manuscripts focused on scientifically based, practical information relevant to all aspects of neurologic rehabilitation. We publish unsolicited papers detailing original work/research that covers the full life span and range of neurological disabilities including stroke, spinal cord injury, traumatic brain injury, neuromuscular disease and other neurological disorders. We also publish thematically organized issues that focus on specific clinical disorders, types of therapy and age groups. Proposals for thematic issues and suggestions for issue editors are welcomed.