Yue Wang, Li Yu, Ruifei Zheng, Xiaofeng Lv, Jie Zhang, Weiwei Jiang, Weibing Tang
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引用次数: 0
Abstract
Purpose: The aim of this study is to follow up the psycho-behavioural development of children with SBS and to analyse the influencing factors affecting the children's psycho-behavioural development.
Methods: Clinical information about 86 children with SBS was retrospectively collected through the hospital electronic medical record system. The ASQ-3 was used to assess the psycho-behavioural developmental outcomes of the children. Spearman's correlation coefficient, Kruskal Wallis H test, logistic regression analysis were used to find the risk factors affecting the psycho-behavioural development of the children through SPSS 27.0 statistical software.
Results: Total bilirubin level was an influencing factor in gross motor (OR = 1.013, p = 0.010) and fine motor development (OR = 1.012, p = 0.044). ALT (OR = 1.007, p = 0.041) and AST (OR = 0.995, p = 0.021) were the influencing factors of gross motor development. High direct bilirubin (OR = 1.018, p = 0.034) was a risk factor for fine motor development. The presence or absence of IFALD (OR = 5.883, p = 0.034) during hospitalisation affected children's communication development. Preservation of the ileocecal junction during surgeries was beneficial for the development of communication (OR = 0.138, p = 0.007), problem-solving (OR = 0.117, p = 0.003), and personal-socialisation (OR = 0.119, p < 0.001). Absence of sepsis (OR = 0.227, p = 0.040) was a protective factor for the personal-socialisation development of the children. Retinol-binding protein was a protective factor in the communication (OR = 0.842, p = 0.012) and personal-socialisation (OR = 0.896, p = 0.014) domains of the children.
Conclusion: Our study finds a possible association between the liver function, nutritional status, retention of the ileocecal junction during surgeries and psycho-behavioural development in children with SBS, providing recommendations for future clinical interventions and treatments.
期刊介绍：
Pediatric Surgery International is a journal devoted to the publication of new and important information from the entire spectrum of pediatric surgery. The major purpose of the journal is to promote postgraduate training and further education in the surgery of infants and children.
The contents will include articles in clinical and experimental surgery, as well as related fields. One section of each issue is devoted to a special topic, with invited contributions from recognized authorities. Other sections will include:
-Review articles-
Original articles-
Technical innovations-
Letters to the editor
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