Yao-Chung Yang , Chun-Hao Yin , Pei-Chin Lin , Yow-Ling Shiue
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引用次数: 0
Abstract
Background
Sarcopenia is associated with poor prognosis in patients with acute stroke. While temporalis muscle thickness (TMT) and area (TMA) have been studied in various conditions, their association with stroke prognosis remains unclear.
Methods
To investigate the validity of TMT and TMA as poststroke outcome predictors, we performed a comprehensive search of the PubMed, CENTRAL, and Embase databases to identify pertinent studies published up to October 31, 2024. A meta-analysis of the pooled estimates of the temporalis muscle predictors was conducted, and the evidence quality was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach.
Results
This meta-analysis included 15 studies and revealed that both TMT and TMA were associated with functional outcomes and dysphagia risk in patients with stroke. Specifically, patients with better functional outcome had higher TMT value (mean difference [MD] = 0.84 mm, 95% confidence interval [CI] = 0.55–1.13, I2 = 45%). Likewise, patients with better functional outcomes had larger TMA values (MD = 65.99 mm2, 95% CI = 0.41–1.06, I2 = 85%). A lower TMT value at stroke onset was associated with increased dysphagia risk (MD = 1.63 mm, 95% CI = 0.74–2.52, I2 = 50%). Subgroup analyses showed that the association between TMT and functional outcome was more evident in individuals aged 50 years or older and in Asian populations, with no significant differences observed between sexes. The certainty of evidence according to GRADE assessment ranged from low to moderate.
Conclusions
TMT and TMA measurements obtained from routine neuroimaging may serve as useful reference markers for functional prognosis in stroke patients.
期刊介绍:
There is increasing scientific and clinical interest in the interactions of nutrition and health as part of the aging process. This interest is due to the important role that nutrition plays throughout the life span. This role affects the growth and development of the body during childhood, affects the risk of acute and chronic diseases, the maintenance of physiological processes and the biological process of aging. A major aim of "The Journal of Nutrition, Health & Aging" is to contribute to the improvement of knowledge regarding the relationships between nutrition and the aging process from birth to old age.