Critical Illness-Associated Cerebral Microbleed in a Young Patient With Sickle Cell Disease.

IF 1 Q3 MEDICINE, GENERAL & INTERNAL
Cureus Pub Date : 2025-06-16 eCollection Date: 2025-06-01 DOI:10.7759/cureus.86166
Ruth Pius, Moustafa M Shaaban, Jose A Suarez
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Abstract

Critical illness-associated cerebral microbleeds (CICMs) are a recent clinical entity described as occurring in critically ill and mechanically ventilated patients, especially those with a risk of cerebral hypoxia. CICMs have been associated with progressive cognitive decline, and the management is supportive. We report the case of a 29-year-old male patient with sickle cell disease admitted for vaso-occlusive crises, which was complicated by multifocal pneumonia, and acute chest syndrome requiring intensive care unit admission and mechanical ventilation. He was noted to have poor mental status off sedation, with a brain MRI showing innumerable microhemorrhages throughout the bilateral cerebral and cerebellar hemispheres, suggestive of CICM.

年轻镰状细胞病患者的危重疾病相关脑微出血
危重性疾病相关脑微出血(cicm)是最近出现在危重症和机械通气患者中的一种临床现象,特别是那些有脑缺氧风险的患者。cicm与进行性认知能力下降有关,管理是支持的。我们报告一例29岁男性镰状细胞病患者,因血管闭塞危像入院,并发多灶性肺炎和急性胸部综合征,需要重症监护病房和机械通气。在服用镇静剂后,他的精神状态很差,大脑MRI显示双侧大脑和小脑半球有无数的微出血,提示CICM。
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