Neurological Behcet's disease with transverse myelitis in an adolescent: A case report.

Abstract

Neurological Behcet's disease is a rare systemic vasculitis marked by recurrent oral or genital ulcers, eye manifestations of uveitis or retinal vasculitis, and skin lesions. This report details a case of neurological Behcet's disease in a 14-year-old Somali male who presented with bilateral pan uveitis, genital ulcers, altered level of consciousness, and seizure. The patient met 2014 International Criteria for Behcet Disease. Magnetic resonance imaging demonstrated abnormal hyperintensity to bilateral hippocampi and mesial temporal lobes. Spine magnetic resonance imaging revealed patchy long segment T2 signal abnormality of the central spinal cord and patchy enhancement at T6. He received IV methylprednisolone, IV infliximab, and then oral prednisone. This case demonstrates children with neurological Behcet's disease can present with hippocampus involvement and transverse myelitis. Physicians should consider neurological Behcet's disease in pediatric patients presenting with altered level of consciousness or seizure. It illustrates the importance of timely intervention in mitigating the neurological complications associated with neurological Behcet's disease.