Delayed uveitis after implantable Collamer lens Implantation caused by COVID-19 infection: a case report.

IF 1.7 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
American journal of translational research Pub Date : 2025-05-15 eCollection Date: 2025-01-01 DOI:10.62347/HHLS1617
Yan Sun, Huiying Wu, Xingke Yan, Jibo Zhou, Tianyue Niu, Jie Zhu
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Abstract

This report presents a case of uveitis secondary to ankylosing spondylitis (AS) with abnormal exudative deposits and pigment adhesion on the surface of an implantable Collamer lens (ICL) in a highly myopic eye following coronavirus disease 2019 (COVID-19) infection. The etiology and treatment were analyzed. A 22-year-old male presented with decreased visual acuity in the right eye, having undergone bilateral ICL implantation for high myopia 22 months prior. During the COVID-19 pandemic, he developed ocular exudation, pigment deposition, and vision deterioration, with a confirmed diagnosis of AS. Therapeutic interventions included anti-inflammatory, antiviral, and corticosteroid therapies. Postoperative uveitis secondary to AS following ICL implantation represents a rare complication. COVID-19 infection and concurrent systemic autoimmune disorders were identified as risk factors for secondary iridocyclitis. Immunological testing confirmed AS diagnosis. Treatment with sodium hyaluronate eye drops, ganciclovir ophthalmic gel, and systemic corticosteroids improved symptoms; however, persistent punctate exudates and pigment deposits on the ICL surface exhibited limited resolution. For patients with systemic autoimmune diseases or virus-induced uveitis undergoing ICL implantation, preoperative immunological screening should be actively performed to minimize postoperative complications. Early comprehensive therapy is critical to prevent progressive vision loss and rare transparency alterations of the ICL surface caused by pigment-laden exudates.

新型冠状病毒感染致人工晶体植入术后迟发性葡萄膜炎1例。
报告1例强直性脊柱炎(AS)继发葡萄膜炎,伴冠状病毒病2019 (COVID-19)感染后高度近视眼植入式屈光体(ICL)表面异常渗出沉积物和色素粘连。分析其病因及治疗方法。22岁男性,22个月前因高度近视行双侧ICL植入术,右眼视力下降。在2019冠状病毒病大流行期间,患者出现眼部渗出、色素沉积、视力下降,确诊为AS。治疗干预包括抗炎、抗病毒和皮质类固醇治疗。ICL植入术后继发AS的葡萄膜炎是一种罕见的并发症。COVID-19感染和并发的全身自身免疫性疾病被确定为继发性虹膜睫状体炎的危险因素。免疫检查证实AS诊断。用透明质酸钠滴眼液、更昔洛韦眼用凝胶和全身皮质类固醇治疗可改善症状;然而,ICL表面持续的点状渗出物和色素沉积表现出有限的分辨率。对于患有全身性自身免疫性疾病或病毒性葡萄膜炎的患者行ICL植入术,术前应积极进行免疫筛查,尽量减少术后并发症。早期综合治疗对于预防进行性视力丧失和罕见的由色素渗出物引起的ICL表面透明度改变至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
American journal of translational research
American journal of translational research ONCOLOGY-MEDICINE, RESEARCH & EXPERIMENTAL
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