Acupuncture for neurodegenerative diseases: mechanisms, efficacy, and future research directions.

IF 1.7 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
American journal of translational research Pub Date : 2025-05-15 eCollection Date: 2025-01-01 DOI:10.62347/QFJO6227
Xin Tang, Chen Wang, Shan Tian, Hejun Wen, Hong Zhang
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引用次数: 0

Abstract

In recent years, acupuncture has shown good therapeutic efficacy in treating neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis. Studies have demonstrated that acupuncture alleviates symptoms primarily by suppressing neuroinflammation, enhancing autophagy, improving synaptic plasticity, and optimizing mitochondrial function. As molecular research advances, the underlying mechanisms of acupuncture in these conditions have become increasingly clear. This review summarizes recent progress in understanding the efficacy and molecular mechanisms of acupuncture in neurodegenerative diseases, providing a theoretical support for its clinical application.

针刺治疗神经退行性疾病:机制、疗效及未来研究方向。
近年来,针灸在治疗阿尔茨海默病、帕金森病、肌萎缩侧索硬化症、多发性硬化症等神经退行性疾病方面显示出良好的疗效。研究表明,针灸主要通过抑制神经炎症、增强自噬、改善突触可塑性和优化线粒体功能来缓解症状。随着分子研究的进展,针灸治疗这些疾病的潜在机制越来越清楚。本文综述了近年来针刺治疗神经退行性疾病的疗效及其分子机制的研究进展,为针刺治疗神经退行性疾病的临床应用提供理论支持。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
American journal of translational research
American journal of translational research ONCOLOGY-MEDICINE, RESEARCH & EXPERIMENTAL
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552
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