Dimitri J Pournaras, João Diogo da Rocha Fernandes, Sara Holloway, Alistair Marsland, Abd A Tahrani, Silvia Capucci
{"title":"Modelled Weight Loss in an English Population Eligible for Bariatric Surgery: A Retrospective Open Cohort Study.","authors":"Dimitri J Pournaras, João Diogo da Rocha Fernandes, Sara Holloway, Alistair Marsland, Abd A Tahrani, Silvia Capucci","doi":"10.1007/s12325-025-03267-8","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>In this study, we aimed to quantify the economic consequences of limited access to obesity treatment and estimate the effect of modelled weight loss in a population who were eligible for bariatric surgery.</p><p><strong>Methods: </strong>This was a retrospective open cohort study using data from the Discover database (1 January 2010-31 December 2019). Index was the first day that individuals were aged ≥ 18 years and eligible for bariatric surgery [body mass index (BMI) ≥ 40.0 kg/m<sup>2</sup> (obesity class III), or 35.0-39.9 kg/m<sup>2</sup> (obesity class II) and an obesity-related complication]. Time to surgery, healthcare costs and the impact of modelled weight loss over 2 years on estimated healthcare costs were assessed.</p><p><strong>Results: </strong>In total, 137,184 individuals were eligible for bariatric surgery, of whom 3241 (2.4%) ultimately received surgery during follow-up. Individuals who received surgery were slightly younger, and were more likely to be women and white, than the population eligible for surgery. Overall, 36.6% of individuals underwent surgery ≥ 4 years after they became eligible. Mean annual per-person healthcare costs increased 75% between year 1 and year 8 of the period before surgery in this group [from 1150 British pound sterling (GBP) to 2013 GBP]. Modelled weight loss of 10% would result in 58.3% of eligible individuals transitioning to obesity class I after 2 years, with only 12.2% remaining in obesity class III, resulting in a 14.3% reduction in healthcare costs. Greater degrees of weight loss were associated with greater estimated reductions in BMI and cost.</p><p><strong>Conclusion: </strong>Delays to prompt weight management support appear to be associated with increasing healthcare costs, which could be mitigated by improving access to weight management.</p>","PeriodicalId":7482,"journal":{"name":"Advances in Therapy","volume":" ","pages":""},"PeriodicalIF":3.4000,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Therapy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s12325-025-03267-8","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: In this study, we aimed to quantify the economic consequences of limited access to obesity treatment and estimate the effect of modelled weight loss in a population who were eligible for bariatric surgery.
Methods: This was a retrospective open cohort study using data from the Discover database (1 January 2010-31 December 2019). Index was the first day that individuals were aged ≥ 18 years and eligible for bariatric surgery [body mass index (BMI) ≥ 40.0 kg/m2 (obesity class III), or 35.0-39.9 kg/m2 (obesity class II) and an obesity-related complication]. Time to surgery, healthcare costs and the impact of modelled weight loss over 2 years on estimated healthcare costs were assessed.
Results: In total, 137,184 individuals were eligible for bariatric surgery, of whom 3241 (2.4%) ultimately received surgery during follow-up. Individuals who received surgery were slightly younger, and were more likely to be women and white, than the population eligible for surgery. Overall, 36.6% of individuals underwent surgery ≥ 4 years after they became eligible. Mean annual per-person healthcare costs increased 75% between year 1 and year 8 of the period before surgery in this group [from 1150 British pound sterling (GBP) to 2013 GBP]. Modelled weight loss of 10% would result in 58.3% of eligible individuals transitioning to obesity class I after 2 years, with only 12.2% remaining in obesity class III, resulting in a 14.3% reduction in healthcare costs. Greater degrees of weight loss were associated with greater estimated reductions in BMI and cost.
Conclusion: Delays to prompt weight management support appear to be associated with increasing healthcare costs, which could be mitigated by improving access to weight management.
期刊介绍：
Advances in Therapy is an international, peer reviewed, rapid-publication (peer review in 2 weeks, published 3–4 weeks from acceptance) journal dedicated to the publication of high-quality clinical (all phases), observational, real-world, and health outcomes research around the discovery, development, and use of therapeutics and interventions (including devices) across all therapeutic areas. Studies relating to diagnostics and diagnosis, pharmacoeconomics, public health, epidemiology, quality of life, and patient care, management, and education are also encouraged.
The journal is of interest to a broad audience of healthcare professionals and publishes original research, reviews, communications and letters. The journal is read by a global audience and receives submissions from all over the world. Advances in Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an international and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. This inclusive approach allows the journal to assist in the dissemination of all scientifically and ethically sound research.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
