Sliding mode control with stochastic modeling and mobility interaction for managing epidemic spread in high-population regions

IF 2.4 Q3 INFECTIOUS DISEASES
Dewi Suhika , Roberd Saragih , Dewi Handayani , Mochamad Apri
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引用次数: 0

Abstract

Managing infectious disease transmission in high-mobility regions is a critical challenge due to dynamic population interactions and elevated transmission risks. This study develops a stochastic epidemiological model to simulate disease spread between two densely populated provinces in Indonesia, Jakarta and West Java. A robust sliding mode control (SMC) framework is proposed and integrated with an Extended Kalman Filter (EKF) to estimate key epidemiological parameters in real time using limited observable data. The proposed framework functions as a theoretical and simulation-based tool to evaluate the potential effects of vaccination and isolation strategies. Although full-state variables are not directly measurable in practice, the EKF allows for the estimation of unobservable parameters, thereby enabling control analysis under uncertainty. Simulation results demonstrate that the SMC strategy significantly reduces infection levels in both provinces, achieving reductions of 84.45 % and 63.94 % in Jakarta, and 98.83 % and 58.35 % in West Java, for the original and Omicron variants, respectively. By incorporating stochasticity, the model captures natural fluctuations and mismatched uncertainties in epidemic progression. This work contributes a conceptual control framework that integrates EKF and SMC for managing stochastic epidemic systems. While the approach is not directly implementable for real-time policymaking, it offers valuable insight into disease dynamics and the potential impact of control strategies under limited observability. These findings support the use of data-driven control simulations for scenario evaluation and policy guidance in complex, uncertain epidemic settings.
基于随机建模和流动性相互作用的滑模控制在人口密集地区的流行病传播管理
由于人口动态互动和传播风险增加,在高流动性地区管理传染病传播是一项重大挑战。本研究开发了一个随机流行病学模型来模拟印度尼西亚雅加达和西爪哇两个人口稠密省份之间的疾病传播。提出了一种鲁棒滑模控制框架,并将其与扩展卡尔曼滤波(EKF)相结合,利用有限的可观测数据实时估计关键的流行病学参数。该框架作为一种基于理论和模拟的工具来评估疫苗接种和隔离策略的潜在影响。虽然在实践中不能直接测量全状态变量,但EKF允许估计不可观测参数,从而实现不确定性下的控制分析。模拟结果表明,SMC策略显著降低了两省的感染水平,雅加达的原始和Omicron变体分别减少了84.45%和63.94%,西爪哇分别减少了98.83%和58.35%。通过纳入随机性,该模型捕获了流行病进展中的自然波动和不匹配的不确定性。这项工作为管理随机流行病系统提供了一个整合EKF和SMC的概念控制框架。虽然该方法不能直接用于实时决策,但它提供了对疾病动态和在有限可观测性下控制策略的潜在影响的宝贵见解。这些发现支持在复杂、不确定的流行病环境中使用数据驱动的控制模拟进行情景评估和政策指导。
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来源期刊
Parasite Epidemiology and Control
Parasite Epidemiology and Control Medicine-Infectious Diseases
CiteScore
5.70
自引率
3.10%
发文量
44
审稿时长
17 weeks
期刊介绍: Parasite Epidemiology and Control is an Open Access journal. There is an increasing amount of research in the parasitology area that analyses the patterns, causes, and effects of health and disease conditions in defined populations. This epidemiology of parasite infectious diseases is predominantly studied in human populations but also spans other major hosts of parasitic infections and as such this journal will have a broad remit. We will focus on the major areas of epidemiological study including disease etiology, disease surveillance, drug resistance and geographical spread and screening, biomonitoring, and comparisons of treatment effects in clinical trials for both human and other animals. We will also look at the epidemiology and control of vector insects. The journal will also cover the use of geographic information systems (Epi-GIS) for epidemiological surveillance which is a rapidly growing area of research in infectious diseases. Molecular epidemiological approaches are also particularly encouraged.
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