Surveillance of antibiotic resistance in Neisseria gonorrhoeae in the WHO Western Pacific Region, 2000.

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Abstract

A long-term program of surveillance of antimicrobial resistance in Neisseria gonorrhoeae isolated in the World Health Organization's Western Pacific Region (WHO WPR GASP) continued in 2000. About 11,000 gonococci were examined in 15 focal points. Widespread resistance to the penicillin group of antibiotics was confirmed. Resistance to quinolone antibiotics, already widely dispersed, increased further with a shift to higher levels of resistance in many centres. Gonococci with decreased susceptibility to third generation cephalosporins were observed in 5 centres. Spectinomycin resistance was infrequently encountered. Options for cheap and effective treatment of gonorrhoea in the WPR are increasingly limited.

2000年世卫组织西太平洋区域淋病奈瑟菌抗生素耐药性监测。
在世界卫生组织西太平洋区域分离的淋病奈瑟菌耐药性长期监测规划于2000年继续进行。在15个焦点地区检查了约11,000个淋球菌。证实对青霉素类抗生素的广泛耐药。已经广泛传播的喹诺酮类抗生素耐药性进一步增加,在许多中心转向更高的耐药水平。在5个中心观察到淋球菌对第三代头孢菌素的敏感性降低。大观霉素耐药少见。在西非地区,淋病廉价和有效治疗的选择越来越有限。
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