Psychological Outcomes in a Cohort of Portuguese Living Kidney Donors

IF 0.8 4区医学 Q4 IMMUNOLOGY

Transplantation proceedings Pub Date : 2025-09-01 DOI:10.1016/j.transproceed.2025.05.006

Manuela Almeida , Inês Carvalho Frade , Alexandra Sousa , La Salete Martins , Miguel Silva Ramos , Jorge Malheiro , Isabel Fonseca , Alice Lopes

{"title":"Psychological Outcomes in a Cohort of Portuguese Living Kidney Donors","authors":"Manuela Almeida , Inês Carvalho Frade , Alexandra Sousa , La Salete Martins , Miguel Silva Ramos , Jorge Malheiro , Isabel Fonseca , Alice Lopes","doi":"10.1016/j.transproceed.2025.05.006","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>The psychosocial aspects of living kidney donation remain a challenge nowadays. We sought to evaluate the psychological outcomes of donation in a cohort of living kidney donors (LKDs).</div></div><div><h3>Material and methods</h3><div><span>LKDs who underwent nephrectomy<span> from January 2018 to December 2019 completed a predonation psychosocial assessment followed by a postdonation evaluation using 36-Item Short Form (SF-36) and Hospital Anxiety and Depression Scale forms in May 2022. Mean scores were compared before and after the donation using the paired </span></span><em>t</em>-test. Peason’s correlation tested the relationship between anxiety and depression scores and relevant variables.</div></div><div><h3>Results</h3><div>Forty-four LKDs were included. Most were female (68.2%), aged 47.3 ± 10.3 years, 52.3% were genetically related, and 63.6% were compatible and donated directly to their recipients. Overall, we observed a statistically significant reduction postdonation in various components of SF-36: physical functioning (<em>P</em> = .037), bodily pain (<em>P</em> = .003), vitality (<em>P</em> = .023), social functioning (<em>P</em> = .023), and mental health (<em>P</em> = .006). Only LKDs who experienced stressful life events (<em>n</em> = 19), showed significant reductions in some SF-36 domains: physical functioning (<em>P</em> = .012), physical role (<em>P</em> = .028), bodily pain (<em>P</em> = .006), and mental health (<em>P</em> = .009). Depression scores increased significantly postdonation (<em>P</em><span> = .029) but lacked clinical significance. Additionally, there was a positive and significant correlation between predonation depression scores and postdonation anxiety levels postdonation.</span></div></div><div><h3>Conclusions</h3><div>Living donation is usually a safe procedure regarding psychosocial aspects. Nonetheless, some LKDs, particularly those with medical complications or stressful live events, may face adverse emotional impacts, Therefore, transplant professionals must screen, assess, and provide psychosocial support before and after donation.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"57 7","pages":"Pages 1284-1290"},"PeriodicalIF":0.8000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Transplantation proceedings","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S004113452500274X","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"IMMUNOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background

The psychosocial aspects of living kidney donation remain a challenge nowadays. We sought to evaluate the psychological outcomes of donation in a cohort of living kidney donors (LKDs).

Material and methods

LKDs who underwent nephrectomy from January 2018 to December 2019 completed a predonation psychosocial assessment followed by a postdonation evaluation using 36-Item Short Form (SF-36) and Hospital Anxiety and Depression Scale forms in May 2022. Mean scores were compared before and after the donation using the paired t-test. Peason’s correlation tested the relationship between anxiety and depression scores and relevant variables.

Results

Forty-four LKDs were included. Most were female (68.2%), aged 47.3 ± 10.3 years, 52.3% were genetically related, and 63.6% were compatible and donated directly to their recipients. Overall, we observed a statistically significant reduction postdonation in various components of SF-36: physical functioning (P = .037), bodily pain (P = .003), vitality (P = .023), social functioning (P = .023), and mental health (P = .006). Only LKDs who experienced stressful life events (n = 19), showed significant reductions in some SF-36 domains: physical functioning (P = .012), physical role (P = .028), bodily pain (P = .006), and mental health (P = .009). Depression scores increased significantly postdonation (P = .029) but lacked clinical significance. Additionally, there was a positive and significant correlation between predonation depression scores and postdonation anxiety levels postdonation.

Conclusions

Living donation is usually a safe procedure regarding psychosocial aspects. Nonetheless, some LKDs, particularly those with medical complications or stressful live events, may face adverse emotional impacts, Therefore, transplant professionals must screen, assess, and provide psychosocial support before and after donation.

查看原文本刊更多论文

葡萄牙活体肾供者队列的心理结果。

背景：目前，活体肾脏捐献的社会心理方面仍然是一个挑战。我们试图评估一组活体肾供者（LKDs）捐献的心理结果。材料和方法：2018年1月至2019年12月接受肾切除术的lkd完成捐赠前心理社会评估，并于2022年5月使用36项简短表格（SF-36）和医院焦虑和抑郁量表完成捐赠后评估。使用配对t检验比较捐献前后的平均得分。皮森的相关性测试了焦虑和抑郁得分与相关变量之间的关系。结果：共纳入44例lkd。多数为女性（68.2%），年龄为47.3±10.3岁，52.3%为遗传相关，63.6%为配型，直接捐献给受体。总的来说，我们观察到捐献后SF-36的各个组成部分的统计学显著降低：身体功能（P = 0.037）、身体疼痛（P = 0.003）、活力（P = 0.023）、社会功能（P = 0.023）和心理健康（P = 0.006）。只有经历过压力生活事件的lsd （n = 19）在某些SF-36领域表现出显著的降低：身体功能（P = 0.012）、身体角色（P = 0.028）、身体疼痛（P = 0.006）和心理健康（P = 0.009）。捐献后抑郁评分显著升高（P = 0.029），但缺乏临床意义。此外，捐赠前抑郁评分与捐赠后焦虑水平之间存在显著正相关。结论：就社会心理方面而言，活体捐赠通常是一种安全的程序。尽管如此，一些LKDs，特别是那些有医疗并发症或有压力的生活事件的患者，可能会面临不利的情绪影响，因此，移植专业人员必须在捐赠前后筛查、评估和提供社会心理支持。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Transplantation proceedings 医学-免疫学

CiteScore

1.70

自引率

0.00%

发文量

502

审稿时长

60 days

期刊介绍： Transplantation Proceedings publishes several different categories of manuscripts, all of which undergo extensive peer review by recognized authorities in the field prior to their acceptance for publication. The first type of manuscripts consists of sets of papers providing an in-depth expression of the current state of the art in various rapidly developing components of world transplantation biology and medicine. These manuscripts emanate from congresses of the affiliated transplantation societies, from Symposia sponsored by the Societies, as well as special Conferences and Workshops covering related topics. Transplantation Proceedings also publishes several special sections including publication of Clinical Transplantation Proceedings, being rapid original contributions of preclinical and clinical experiences. These manuscripts undergo review by members of the Editorial Board. Original basic or clinical science articles, clinical trials and case studies can be submitted to the journal?s open access companion title Transplantation Reports.