A Case of Methemoglobinemia and Hemolysis from Sodium Chlorite Ingestion.

IF 1.2 Q2 MEDICINE, GENERAL & INTERNAL
Jessica Liu, Matthew Patel, Marisa Vigna, Mark Keith Hewitt, Wendy Lim
{"title":"A Case of Methemoglobinemia and Hemolysis from Sodium Chlorite Ingestion.","authors":"Jessica Liu, Matthew Patel, Marisa Vigna, Mark Keith Hewitt, Wendy Lim","doi":"10.3121/cmr.2025.1954","DOIUrl":null,"url":null,"abstract":"<p><p>Sodium chlorite is a household and industrial cleaning agent that can cause oxidative stress leading to methemoglobinemia and severe hemolysis when ingested. There is a scarcity of published literature reporting this in humans. We report a case of intentional sodium chlorite ingestion for homeopathic purposes that resulted in methemoglobinemia and hemolysis, requiring admission to the intensive care unit. Following successful treatment with methylene blue, the patient developed worsening hemolytic activity. Outpatient testing later revealed she was non- glucose-6-phosphate dehydrogenase (G6PD) deficient. Hemolysis precipitated by methylene blue is an underrecognized side effect that can be observed in individuals both with and without G6PD deficiency.</p>","PeriodicalId":47429,"journal":{"name":"Clinical Medicine & Research","volume":"23 1","pages":"21-25"},"PeriodicalIF":1.2000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12172662/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Medicine & Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3121/cmr.2025.1954","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0

Abstract

Sodium chlorite is a household and industrial cleaning agent that can cause oxidative stress leading to methemoglobinemia and severe hemolysis when ingested. There is a scarcity of published literature reporting this in humans. We report a case of intentional sodium chlorite ingestion for homeopathic purposes that resulted in methemoglobinemia and hemolysis, requiring admission to the intensive care unit. Following successful treatment with methylene blue, the patient developed worsening hemolytic activity. Outpatient testing later revealed she was non- glucose-6-phosphate dehydrogenase (G6PD) deficient. Hemolysis precipitated by methylene blue is an underrecognized side effect that can be observed in individuals both with and without G6PD deficiency.

食入亚氯酸钠致高铁血红蛋白血症及溶血1例。
亚氯酸钠是一种家用和工业清洗剂,当摄入时会引起氧化应激,导致高铁血红蛋白血症和严重的溶血。在人类中发表的文献报道很少。我们报告一个顺势疗法的目的故意摄入亚氯酸钠的情况下,导致高铁血红蛋白血症和溶血,需要入院重症监护病房。亚甲蓝治疗成功后,患者溶血活性恶化。门诊检查显示她缺乏非葡萄糖-6-磷酸脱氢酶(G6PD)。亚甲基蓝引起的溶血是一种未被认识到的副作用,在G6PD缺乏症患者和非G6PD缺乏症患者中都可以观察到。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Clinical Medicine & Research
Clinical Medicine & Research MEDICINE, GENERAL & INTERNAL-
CiteScore
1.80
自引率
7.10%
发文量
25
期刊介绍: Clinical Medicine & Research is a peer reviewed publication of original scientific medical research that is relevant to a broad audience of medical researchers and healthcare professionals. Articles are published quarterly in the following topics: -Medicine -Clinical Research -Evidence-based Medicine -Preventive Medicine -Translational Medicine -Rural Health -Case Reports -Epidemiology -Basic science -History of Medicine -The Art of Medicine -Non-Clinical Aspects of Medicine & Science
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信