Association between dietary calcium intake and benign prostatic hyperplasia: a population-based result from NHANES 2003 to 2008.

IF 1.9 3区医学 Q4 ANDROLOGY

Translational andrology and urology Pub Date : 2025-05-30 Epub Date: 2025-05-22 DOI:10.21037/tau-2025-43

Hongyuan Chang, Hao Wang, Anmin Wang, Dongyue Ma, Hui Lv, Di Sun, Ziwei Zhao, Dicheng Luo, Shihao Wang, Jun Guo, Fu Wang

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引用次数: 0

Abstract

Background: Benign prostatic hyperplasia (BPH), as a cause of various lower urinary tract symptoms (LUTS), can improve patients' quality of life when effectively controlled. To elaborate on the effect of dietary calcium intake on BPH, we investigated the association between dietary calcium intake and the risk of BPH using data from the National Health and Nutrition Examination Survey (NHANES).

Methods: Data from the NHANES conducted from 2003 to 2008 were utilized. BPH was identified through self-reported questionnaires, and dietary calcium intake was calculated based on the mean of two 24-hour dietary recall interviews. Multivariable logistic regression analyses were performed to assess the association, supplemented by restricted cubic spline analysis and subgroup analyses.

Results: A total of 590 males aged 40 years and older were included in the study, of whom 138 had BPH. After adjusting for all covariates, a higher dietary calcium intake was associated with an increased risk of BPH [odds ratio (OR), 1.05; 95% confidence interval (CI): 1.01-1.09; P=0.04], and those without hypertension.

Conclusions: The study found a positive association between dietary calcium intake and the risk of BPH among U.S. men aged 40 years and older. High calcium intake may be associated with the occurrence of BPH, particularly in older individuals. These findings underscore the importance of monitoring dietary calcium intake as part of BPH prevention strategies.

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膳食钙摄入量与良性前列腺增生之间的关系：2003年至2008年NHANES基于人群的结果

背景：良性前列腺增生（BPH）是引起各种下尿路症状（LUTS）的原因之一，如果得到有效控制，可以改善患者的生活质量。为了详细说明膳食钙摄入量对BPH的影响，我们利用国家健康与营养检查调查（NHANES）的数据调查了膳食钙摄入量与BPH风险之间的关系。方法：采用2003 ~ 2008年NHANES数据。通过自我报告的问卷来确定BPH，并根据两次24小时饮食回忆访谈的平均值计算膳食钙摄入量。采用多变量logistic回归分析评估相关性，并辅以限制性三次样条分析和亚组分析。结果：共有590名年龄在40岁及以上的男性被纳入研究，其中138人患有前列腺增生。在对所有协变量进行调整后，较高的膳食钙摄入量与BPH风险增加相关[优势比（OR）， 1.05；95%置信区间（CI）： 1.01-1.09；P=0.04]，无高血压者。结论：研究发现，在40岁及以上的美国男性中，膳食钙摄入量与前列腺增生的风险呈正相关。高钙摄入可能与BPH的发生有关，特别是在老年人中。这些发现强调了监测膳食钙摄入量作为BPH预防策略的一部分的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Translational andrology and urology Medicine-Urology

CiteScore

4.10

自引率

5.00%

发文量

期刊介绍： ranslational Andrology and Urology (Print ISSN 2223-4683; Online ISSN 2223-4691; Transl Androl Urol; TAU) is an open access, peer-reviewed, bi-monthly journal (quarterly published from Mar.2012 - Dec. 2014). The main focus of the journal is to describe new findings in the field of translational research of Andrology and Urology, provides current and practical information on basic research and clinical investigations of Andrology and Urology. Specific areas of interest include, but not limited to, molecular study, pathology, biology and technical advances related to andrology and urology. Topics cover range from evaluation, prevention, diagnosis, therapy, prognosis, rehabilitation and future challenges to urology and andrology. Contributions pertinent to urology and andrology are also included from related fields such as public health, basic sciences, education, sociology, and nursing.