Patient Reported Outcomes and Treatment-Associated Complications as a Consideration in Selecting Localized Prostate Cancer Management.

IF 2 Q2 UROLOGY & NEPHROLOGY
Research and Reports in Urology Pub Date : 2025-06-12 eCollection Date: 2025-01-01 DOI:10.2147/RRU.S386383
Tivoli Nguyen, Christine Lightfoot, David May, Jacob W Greenberg, Louis Spencer Krane
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引用次数: 0

Abstract

Localized prostate cancer (PCa) remains the most common noncutaneous cancer in men, with numerous management options tailored to individual patient needs. This review examines the role of patient-reported outcomes (PROs) in guiding the management of localized PCa, focusing on the impact of various treatments on long-term quality of life. Standard therapies, including radical prostatectomy, radiotherapy, and active surveillance, are discussed alongside emerging focal therapies. Each treatment modality presents distinct risks, notably urinary incontinence, erectile dysfunction, bowel issues, and cancer recurrence. Understanding these adverse effects in terms of PROs is critical for patients and healthcare providers to engage in shared decision-making, enabling personalized treatment plans based on clinical outcomes and patient values. The incorporation of PROs into treatment selection emphasizes the significance of balancing oncologic control with functional outcomes, such as sexual, bowel, and urinary health. The importance of patient counseling is underscored, ensuring patients are fully informed about potential complications and long-term implications. This review advocates for personalized, evidence-based management strategies that align therapeutic decisions with individual patient preferences, optimizing both survival and quality of life. Enhanced communication between patients and clinicians, informed by PROs, is critical for minimizing decisional regret and maximizing satisfaction in the management of localized PCa.

患者报告的结果和治疗相关并发症是选择局限性前列腺癌治疗的考虑因素。
局限性前列腺癌(PCa)仍然是男性中最常见的非皮肤癌症,有许多针对个体患者需求的治疗选择。本综述探讨了患者报告结果(pro)在指导局部PCa管理中的作用,重点关注各种治疗对长期生活质量的影响。标准治疗,包括根治性前列腺切除术、放疗和主动监测,与新兴的局灶性治疗一起讨论。每种治疗方式都有不同的风险,特别是尿失禁、勃起功能障碍、肠道问题和癌症复发。从PROs的角度理解这些不良影响对于患者和医疗保健提供者参与共同决策、根据临床结果和患者价值制定个性化治疗计划至关重要。将PROs纳入治疗选择,强调了平衡肿瘤控制与功能结果(如性、肠道和泌尿健康)的重要性。强调患者咨询的重要性,确保患者充分了解潜在的并发症和长期影响。本综述提倡个性化、循证管理策略,使治疗决策与患者个体偏好相一致,优化生存和生活质量。加强患者和临床医生之间的沟通,由专家告知,对于减少决策后悔和最大化局部PCa管理满意度至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Research and Reports in Urology
Research and Reports in Urology UROLOGY & NEPHROLOGY-
CiteScore
3.40
自引率
0.00%
发文量
60
审稿时长
16 weeks
期刊介绍: Research and Reports in Urology is an international, peer-reviewed, open access, online journal. Publishing original research, reports, editorials, reviews and commentaries on all aspects of adult and pediatric urology in the clinic and laboratory including the following topics: Pathology, pathophysiology of urological disease Investigation and treatment of urological disease Pharmacology of drugs used for the treatment of urological disease Although the main focus of the journal is to publish research and clinical results in humans; preclinical, animal and in vitro studies will be published where they will shed light on disease processes and potential new therapies. Issues of patient safety and quality of care will also be considered.
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