Giulia Spotswood, Lukas Dürst, Thomas Fehr, Lita Rogalla von Bieberstein
{"title":"[Paraneoplastic limbic encephalitis - an important differential diagnosis in cases of unclear encephalopathy].","authors":"Giulia Spotswood, Lukas Dürst, Thomas Fehr, Lita Rogalla von Bieberstein","doi":"10.23785/PRAXIS.2025.06.006","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>The diagnostics of autoimmune encephalitides have made significant progress with the recent discovery of numerous tumor-associated and non-tumor-associated autoantibodies targeting neuronal and glial cells. Nevertheless, physicians continue to face major diagnostic and therapeutic challenges posed by this complex disease. This review summarizes the key aspects of the clinical presentation, diagnostics, and therapy of the most common form of autoimmune encephalitis, limbic encephalitis, with a focus on the paraneoplastic forms.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 6","pages":"234-239"},"PeriodicalIF":0.0000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Praxis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23785/PRAXIS.2025.06.006","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: The diagnostics of autoimmune encephalitides have made significant progress with the recent discovery of numerous tumor-associated and non-tumor-associated autoantibodies targeting neuronal and glial cells. Nevertheless, physicians continue to face major diagnostic and therapeutic challenges posed by this complex disease. This review summarizes the key aspects of the clinical presentation, diagnostics, and therapy of the most common form of autoimmune encephalitis, limbic encephalitis, with a focus on the paraneoplastic forms.