Associations Between Postoperative Symptom Clusters and Functional Status in Lung Cancer Patients: A Cross-Sectional Study.

IF 2.5 4区医学 Q3 ONCOLOGY

Cancer Management and Research Pub Date : 2025-06-12 eCollection Date: 2025-01-01 DOI:10.2147/CMAR.S507420

Yali Liu, Siya Lin, Meirong Bai, Huochun Yi

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Abstract

Background: Symptom clusters in cancer symptom management research, providing a scientific basis for developing effective strategies for symptom assessment and intervention aimed at improving patient quality of life and survival.

Objective: To analyze symptom clusters in postoperative lung cancer patients, examine its influenced factor, and explore the relationship between postoperative symptom clusters and functional status in lung cancer patients.

Methods: Between August 2023 and February 2024, 441 lung cancer patients who underwent surgical treatment in the Department of Thoracic Surgery at a tertiary hospital in Xiamen were selected. Data collection included a general information questionnaire, the Postoperative Patient-Reported Outcomes Scale for Early-Stage Lung Cancer Patients, the Tampa Scale for Kinesiophobia (TSK), and the Karnofsky Performance Status Scale (KPSS). Latent class analysis was employed to categorize the self-reported outcomes. Statistical analyses were performed on the relevant factors.

Results: The self-reported postoperative symptoms in lung cancer patients were divided into two groups: high-symptom burden and low-symptom burden. Significant differences were observed between these groups concerning surgery duration, kinesiophobia score, personality traits, KPSS, and the use of analgesic pumps (P <0.005). After adjusting for sex, age, lifestyle, and health status, a multi-model approach confirmed a significant inverse relationship between higher KPSS levels and higher symptom burden (P < 0.001). High-symptom levels are negatively associated with functional status (P <0.005).

Conclusion: Postoperative symptom clusters in lung cancer patients can be specifically categorized into high and low-symptom burdens. Surgery duration, kinesiophobia scores, personality traits, KPSS, and the use of analgesic pumps are significant risk factors affecting symptom burden. Postoperative symptom cluster assessment provides a scientific basis for developing effective management strategies, which may improve functional recovery and long-term outcomes in lung cancer patients.

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肺癌患者术后症状群与功能状态的相关性：一项横断面研究

背景：癌症症状管理研究中的症状聚类，为制定有效的症状评估和干预策略提供科学依据，旨在提高患者的生活质量和生存率。目的：分析肺癌术后患者的症状聚类，探讨其影响因素，探讨肺癌患者术后症状聚类与功能状态的关系。方法：选取2023年8月至2024年2月在厦门市某三级医院胸外科接受手术治疗的肺癌患者441例。数据收集包括一般信息问卷、早期肺癌患者术后患者报告结果量表、运动恐惧症坦帕量表（TSK）和Karnofsky表现状态量表（KPSS）。采用潜类分析对自我报告的结果进行分类。对相关因素进行统计分析。结果：肺癌患者术后自述症状分为高症状负担组和低症状负担组。两组在手术时间、运动恐惧症评分、人格特征、KPSS和镇痛泵使用方面存在显著差异（P < 0.001）。结论：肺癌患者术后症状群可明确分为高症状负担和低症状负担。手术时间、运动恐惧症评分、人格特质、KPSS和镇痛泵的使用是影响症状负担的重要危险因素。术后症状聚类评估可为制定有效的治疗策略提供科学依据，从而改善肺癌患者的功能恢复和远期预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cancer Management and Research Medicine-Oncology

CiteScore

7.40

自引率

0.00%

发文量

448

审稿时长

16 weeks

期刊介绍： Cancer Management and Research is an international, peer reviewed, open access journal focusing on cancer research and the optimal use of preventative and integrated treatment interventions to achieve improved outcomes, enhanced survival, and quality of life for cancer patients. Specific topics covered in the journal include: ◦Epidemiology, detection and screening ◦Cellular research and biomarkers ◦Identification of biotargets and agents with novel mechanisms of action ◦Optimal clinical use of existing anticancer agents, including combination therapies ◦Radiation and surgery ◦Palliative care ◦Patient adherence, quality of life, satisfaction The journal welcomes submitted papers covering original research, basic science, clinical & epidemiological studies, reviews & evaluations, guidelines, expert opinion and commentary, and case series that shed novel insights on a disease or disease subtype.