{"title":"Not Enough Cells: How Insufficient Cytological Specimens Are Mirrored by Reporting Systems - Journey from the Bethesda to the WHO Reporting Systems.","authors":"Ivana Kholová","doi":"10.1159/000546947","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Pap classes have been replaced by organ-specific reporting systems in recent decades; however, part of the cytological specimens is insufficient. The present review summarises how different organ-specific systems define the insufficient category: Both quantitative and qualitative criteria are used. In addition, the sample volume may be evaluated in certain specimens.</p><p><strong>Summary: </strong>The reasons for an insufficient sample may vary and depend either on the lesion itself or the sampling procedure.</p><p><strong>Key messages: </strong>The management recommendations for insufficient specimens improve communication between cytopathologists and treating physicians.</p>","PeriodicalId":6959,"journal":{"name":"Acta Cytologica","volume":" ","pages":"1-27"},"PeriodicalIF":1.6000,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Cytologica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1159/000546947","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PATHOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Pap classes have been replaced by organ-specific reporting systems in recent decades; however, part of the cytological specimens is insufficient. The present review summarises how different organ-specific systems define the insufficient category: Both quantitative and qualitative criteria are used. In addition, the sample volume may be evaluated in certain specimens.
Summary: The reasons for an insufficient sample may vary and depend either on the lesion itself or the sampling procedure.
Key messages: The management recommendations for insufficient specimens improve communication between cytopathologists and treating physicians.
期刊介绍:
With articles offering an excellent balance between clinical cytology and cytopathology, ''Acta Cytologica'' fosters the understanding of the pathogenetic mechanisms behind cytomorphology and thus facilitates the translation of frontline research into clinical practice. As the official journal of the International Academy of Cytology and affiliated to over 50 national cytology societies around the world, ''Acta Cytologica'' evaluates new and existing diagnostic applications of scientific advances as well as their clinical correlations. Original papers, review articles, meta-analyses, novel insights from clinical practice, and letters to the editor cover topics from diagnostic cytopathology, gynecologic and non-gynecologic cytopathology to fine needle aspiration, molecular techniques and their diagnostic applications. As the perfect reference for practical use, ''Acta Cytologica'' addresses a multidisciplinary audience practicing clinical cytopathology, cell biology, oncology, interventional radiology, otorhinolaryngology, gastroenterology, urology, pulmonology and preventive medicine.