NICU-specific bundle for minimizing central line-associated bloodstream infections: Comparative health care costs of interventions.

IF 2.4 3区医学 Q2 INFECTIOUS DISEASES

American journal of infection control Pub Date : 2025-06-15 DOI:10.1016/j.ajic.2025.06.010

Irem Iyigun, Kubra Aykac, Pınar Basar, Zeynep Buyukgullu, Sibel Durak, Hasan Tolga Celik, Sule Yigit, Yasemin Ozsurekci

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引用次数: 0

Abstract

Background: Central line-associated bloodstream infections (CLABSIs) in neonatal intensive care units (NICUs) significantly impact patient outcomes and health care costs. This study evaluates the effect of NICU-specific bundle designed to prevent CLABSIs.

Methods: This retrospective single-center study was conducted at Hacettepe University Faculty of Medicine from March 2020 to August 2021. It was designed to compare 2 periods: pre-intervention and post-intervention period.

Results: The implementation of the bundles led to a significant reduction in infection rates, with CLABSIs decreasing from 29 to 4 per 1,000 central line days in NICU-1 and from 14.2 to 2.6 per 1,000 central line days in NICU-2. This decline was accompanied by an 80% reduction in the average health care cost per patient.

Conclusions: The implementation of a NICU-specific CLABSI prevention bundle significantly reduced infection rates and lowered health care costs by approximately 80% per patient. These findings highlight the effectiveness of structured, multidisciplinary infection control strategies in improving neonatal outcomes and resource utilization.

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减少中央静脉相关血流感染的新生儿重症监护病房特异性捆绑：干预措施的比较医疗成本。

背景：新生儿重症监护病房（NICUs）中央线相关血流感染（CLABSIs）显著影响患者预后和医疗保健费用。本研究评估了nicu专用捆绑包预防clabsi的效果。方法：该回顾性单中心研究于2020年3月至2021年8月在Hacettepe大学医学院进行。其目的是比较干预前和干预后两个阶段。结果：该捆绑包的实施显著降低了感染率，新生儿重症监护病房（NICU-1） clabsi从每1000中心线日29例降至4例，新生儿重症监护病房（NICU-2） clabsi从每1000中心线日14.2例降至2.6例。与此同时，每位患者的平均医疗成本降低了80%。结论：实施针对新生儿重症监护病房的CLABSI预防捆绑包可显著降低感染率，并将每位患者的医疗成本降低约80%。这些发现强调了结构化、多学科感染控制策略在改善新生儿结局和资源利用方面的有效性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American journal of infection control 医学-传染病学

CiteScore

7.40

自引率

4.10%

发文量

479

审稿时长

24 days

期刊介绍： AJIC covers key topics and issues in infection control and epidemiology. Infection control professionals, including physicians, nurses, and epidemiologists, rely on AJIC for peer-reviewed articles covering clinical topics as well as original research. As the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC)