Highly pathogenic avian influenza A (H5N1) virus outbreaks in South America in 2022–2024: a comprehensive review of an ongoing panzootic

IF 2.8 3区医学 Q3 VIROLOGY

Virology Pub Date : 2025-06-11 DOI:10.1016/j.virol.2025.110602

Alfredo Bruno , Doménica de Mora , Maritza Olmedo , Jimmy Garcés , Alfonso Marzal , Miguel Angel Garcia-Bereguiain

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引用次数: 0

Abstract

The outbreaks of highly pathogenic avian influenza A (H5N1) clade 2.3.4.4b in South America, which began in 2022, have had significant repercussions across the continent and have led to significant challenges in animal and public health. This review explores the virus's transmission across South America, highlighting the spread of this panzootic through migratory birds and its severe impact on the poultry industry and various wild species, including mammals. The underreporting of influenza cases in poultry underscores the need for enhanced national regulations and strategies to promote reporting within the productive sector. Additionally, the review emphasizes the necessity for active case finding and genomic surveillance in the animal sector to manage better and control the virus. The economic and public health impacts of a potential future pandemic are also considered, emphasizing the need for strengthened surveillance strategies with the One Health approach to mitigate these risks.

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2022-2024年南美高致病性禽流感A （H5N1）病毒暴发：对正在发生的大流行病的全面审查

高致病性甲型（H5N1）进化分支2.3.4.4b禽流感于2022年开始在南美洲暴发，对整个非洲大陆产生了重大影响，并在动物和公共卫生方面带来了重大挑战。这篇综述探讨了该病毒在南美洲的传播，强调了这种大流行病通过候鸟传播及其对家禽业和包括哺乳动物在内的各种野生物种的严重影响。家禽流感病例的少报突出表明需要加强国家法规和战略，以促进生产部门内的报告。此外，该审查强调有必要在动物部门积极发现病例和进行基因组监测，以便更好地管理和控制该病毒。还考虑了未来可能发生的大流行对经济和公共卫生的影响，强调需要加强监测战略，采用“同一个健康”方针，以减轻这些风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Virology 医学-病毒学

CiteScore

6.00

自引率

0.00%

发文量

157

审稿时长

50 days

期刊介绍： Launched in 1955, Virology is a broad and inclusive journal that welcomes submissions on all aspects of virology including plant, animal, microbial and human viruses. The journal publishes basic research as well as pre-clinical and clinical studies of vaccines, anti-viral drugs and their development, anti-viral therapies, and computational studies of virus infections. Any submission that is of broad interest to the community of virologists/vaccinologists and reporting scientifically accurate and valuable research will be considered for publication, including negative findings and multidisciplinary work.Virology is open to reviews, research manuscripts, short communication, registered reports as well as follow-up manuscripts.